Q: What are the newest, most promising medicines for treating heart disease?
A: There are a lot of new, novel therapies, including PCSK9 inhibitors, which we use in our clinic quite a bit. They are the most powerful cholesterol medications we have to date. They have relatively few side effects and work well.
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There are some new antisense oligoneucleotide inhibitors that we are starting trials for with other institutions to see if we can reduce different components of cholesterol over the next few years.
With heart failure, there’s the introduction of Entresto®, which is a medication that has been on the market now for a year and a half. We’ve had very exciting results with the ability to reduce the effects of heart failure.
Rivaroxaban, which is sold under the brand name Xarelto®, is one of the novel blood thinners that we now use for atrial fibrillation, or AFib, that has been shown to lead to less bleeding for patients who need to get a stent.
— Preventive cardiologist Haitham Ahmed, MD, MPH