Today’s Artificial Hearts Go With the Flow

Who says a heart has to go “thump”? Why not “whizzz”? A new generation of artificial hearts does just that. Today’s continuous flow ventricular assist devices (or VADs) have emerged as one of the few effective treatments for heart failure. They offer hope to late-stage patients who cannot receive or access a transplantable donor heart. … Read More

Clinical Trials: Advancing Medicine, Improving Lives

On any given day, hundreds of clinical research trials are under way at Cleveland Clinic’s Heart and Vascular Institute (HVI) and throughout Cleveland Clinic. These carefully monitored trials are what make medical advancements possible. It is thanks to participants in clinical trials that we can save more lives every day and continue to improve national … Read More

Battling the Enemies of Innovation

Every year, thousands of Americans with life-threatening aortic valve disease are told they are too old, too sick or too frail to undergo reparative surgery. Many hospitals are able to tell these patients what’s wrong with them; the vast majority will also tell them they’re simply out of luck.

The One Innovation That is Curing Diabetes

“First, do no harm.” That’s part of the Hippocratic Oath. Doctors take this very seriously. You don’t intervene where the risk of intervention is greater than the risk of the disease. But the No. 1 innovation on the Cleveland Clinic “Top Ten Medical Innovations” list for 2013 is something Hippocrates never dreamed of: bariatric surgery to treat diabetes.

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Mitral Valve Invention Opens Opportunity to the Inoperable

Some heart patients are too high-risk to undergo surgery, but in the future there could be a new option for these people, thanks to a mitral valve invention coming out of Cleveland Clinic. When the mitral valve is insufficient (leaking), quality of life suffers deeply—patients have difficulty breathing because the abnormal valve blocks blood flow … Read More

Valve Replacement: The Amazing Ring Thing

There are three things that you need to know about tissue-based implantable heart valves. One, they are often preferable to mechanical valves because they don’t require life long blood-thinning. Two, implantation involves suturing the ring into the place where the old valve stood. Three, the leaflets wear out in about 10 years, meaning you eventually … Read More

Artificial SmartHeart Could Help Many

About 2,500 patients in the United States receive a heart transplant annually, and more than 25,000 people die every year while waiting for a donor heart. Cleveland Clinic Biomedical Engineer Leonard Golding, MD, talked to Channel 3 News about the development of the SmartHeart Total Artificial Heart. Designed for long-term, durable use, he says it … Read More

18 Innovations: Discovery of the First Heart Attack Gene

A team of Cleveland Clinic researchers including Qing Wang, PhD, director of the Center for Cardiovascular Genetics, published the discovery of the first gene identified as a cause of coronary artery disease. Dr. Wang and his lab isolated the genetic mutation by studying a single family with inherited heart disease. The researchers speculated that the … Read More

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Renal Treatment Lowers Blood Pressure and Costs

Cleveland Clinic is currently enrolling patients in a trial of a new catheter-based treatment for resistant hypertension called renal denervation. This treatment involves slipping a thin device through the blood vessels to the kidneys to deliver a mild radiofrequency heat that neutralizes certain nerves that are involved in causing hypertension. Hypertension (high blood pressure), of course, is a … Read More

18 Innovations: Novel Stent Grafts for Aneurysms

Nature is amazing. You can look out the window at a tree and get a pretty good idea of what the branching parts of the human vascular system look like – twisting, turning and often irregular. The system’s lack of perfect symmetry has challenged vascular surgeons who treat aortic aneurysms by means of intraluminal stent … Read More