How Your Genes Affect Your Reaction to Drugs

Your doctor prescribes a medication. If you have a high risk of negative side effects, do you ask for something else instead? If you know the drug won’t work well for you, do you request more options? These questions aren’t just hypothetical. They’re at the heart of pharmacogenomics. Pharmacogenomics is the study of how your … Read More

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Q&A: The Future of Genome Sequencing for Newborns

Your genes tell a story of health and disease risk — and they tell that story from the day you are born. With that in mind, interest in genomic sequencing for newborns is rising. In 2013, the National Institutes of Health awarded $25 million to four major research projects examining the practice. More recently, one … Read More

The Epigenetics of Cholesterol, Smoking and Cancer

Our DNA is like an encyclopedia containing multiple volumes of genes. Certain genes are responsible for finding errors in these volumes and fixing them. When genes mutate, errors build up, and disease often follows. But what happens when the light we use to read the encyclopedia goes out? We can’t read in the dark. That’s … Read More

3 Ways Genetic Knowledge is Power

“Patients in waiting.” It’s a term we in the world of genetics hear from time to time. The idea is that for certain conditions where there is no cure — or where it may be years before a patient shows symptoms — genetic testing can cause anxiety without providing steps for care. I don’t believe … Read More

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Tumors Are Unique — Treatments Should Be, Too

By Brian Bolwell, MD Like the people they affect, each and every tumor is unique. Because of this, a “one size fits all” approach to cancer treatment does not work, especially in the most challenging cases. But cancer treatment is changing. Understanding each tumor’s unique composition is leading to treatments based on each individual’s needs. … Read More

No. 2 Innovation: Cancer Treatment Gets Personal (Video)

Cleveland Clinic asked more than 100 of its top experts about the innovations set to reshape healthcare in the coming year. These are their answers — the Top 10 Innovations for 2014. Too often, men and women hear the words “prostate cancer,” “breast cancer,” or “colorectal cancer” from their doctor and immediately think the worst. … Read More