Acetaminophen vs. Ibuprofen: Which Works Better?

Finding the best medicine for aches, pain and fever

Discover when the pain-relieving or fever-fighting abilities of acetaminophen and ibuprofen will benefit you. Here, our experts compare benefits, side effects and toxicity.

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Which over-the-counter fever fighter and pain reliever works better: acetaminophen or ibuprofen?

Sometimes, acetaminophen can be more effective than ibuprofen, and vice versa. At other times, both work equally well. But each medication has risks, and some are significant. Ask your doctor which medication is best and which may be too risky for you. Follow dosage directions carefully, and tell your doctor how often you’re taking painkillers.

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