December 21, 2020

Hair Loss Got You Down? Platelet-Rich Plasma May Regrow It

What to know about PRP treatment for androgenic alopecia

A balding man wearing a plaid shirt and a young child playing together with a toy car racetrack

Are you looking for a hair loss solution? A therapy that promotes healing in injured joints may help restore your lost hair.

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About 50 million American men and 30 million women have male- or female-pattern baldness. It can begin early in life, but is much more common after the age of 50, when more than 50% of men will experience some kind of hair loss.

However, an emerging treatment — platelet-rich plasma (PRP) therapy — appears to help regrow lost hair. And, there are virtually no side effects from PRP, except for a mild feeling of pressure at the injection site, says dermatologist Shilpi Khetarpal, MD.

How does PRP therapy work?

Physicians began using PRP therapy about a decade ago to speed up the healing process in damaged joints after injury or surgery.

During the treatment, a technician draws your blood and spins it in a centrifuge to separate out the platelets and plasma. Doctors then inject the plasma, which helps repair blood vessels, promote cell growth and wound healing, and stimulate collagen production.

Doctors began using PRP in dermatology after researchers found that high concentrations of platelets in plasma cells help promote hair growth by prolonging the growing phase of the hair cycle.

Doctors inject plasma into the scalp where hair loss has occurred. They typically administer injections monthly for three months, then spread them out over about three or four months for up to two years. The injection schedule will depend on your genetics, pattern and amount of hair loss, age and hormones.

Because the treatment is cosmetic, insurance does not cover the procedure, Dr. Khetarpal says. The cost ranges between $500 and $1,000 per injection session.

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How does PRP therapy compare with other options?

Other treatments for hair loss currently on the market are often more problematic for many patients, Dr. Khetarpal says.

There are two FDA-approved medications for treating hair loss: finasteride and minoxidil. But you must take these drugs consistently over time and results are inconsistent, she says.

Each drug also sometimes has side effects:

  • Minoxidil may cause dryness and itching on the scalp.
  • Finasteride may cause sexual dysfunction in men.

Hair transplantation is another option, but it requires cuts in the scalp and recovery time is longer, she says.

Because it is a surgical procedure, doctors typically recommend hair transplantation only for those who have dramatic hair loss. A transplant is also more costly and leaves scars. Doctors can perform PRP therapy prior to transplantation, which can provide better results with more dense hair growth, Dr. Khetarpal says.

Researchers see promising results

Recent research bears out the potential of PRP therapy.

In a 2014 study, researchers in India looked at men with male-pattern baldness who used both approved medications, but saw little change in their hair growth.

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After four PRP treatments, they had about 30% more growth in thinning areas.

A 2017 study out of Italy also found male patients had increased hair and density in areas where doctors used PRP therapy.

Dr. Khetarpal says it takes about three months to see an improvement. After that time, most of her patients – both male and female – have regrown 30% to 40% of the hair they’ve lost.

What makes you a good candidate for PRP therapy?

Part of the success of PRP comes from selecting the right patients for therapy, Dr. Khetarpal says. PRP is safe and effective for many people. However, you should not have PRP therapy if you fall into either of these groups:

  • If you have an underlying disorder such as thyroid disease or lupus, you aren’t likely to have good results because these conditions will continue to cause hair loss over time.
  • If you are on blood thinners, your platelets won’t work as effectively and the procedure is not as effective.

PRP therapy works better if your hair loss is recent. It is more challenging to “wake up” hair follicles that have been dormant for a long time, Dr. Khetarpal says.

“I tell people I can get your hair back to what it was five years ago,” she says. “If your hair loss is older, you may see some recovery, but it’s likely not worth your investment of time and money.”

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