August 11, 2019/Digestive

Important Things To Know After a Hepatitis C Diagnosis

Treatment options are better than ever

Liver with hepatitis C illustration

If a blood test reveals that you have a hepatitis C infection, this can be shocking and unsettling news. You might feel confused, especially if you don’t look or feel sick. You might have no idea how you got it. And you might not have even realized you were at risk to begin with.


Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

The first step is to take a deep breath. Hepatitis C is a potentially serious liver infection, but there are very effective treatments.

“The past five years has really been a revolution in the treatment of hepatitis C,” says liver specialist Christina Lindenmeyer, MD.

It’s also important to know that you’re not alone in this experience. The CDC estimates that nearly 2.4 million Americans live with this disease — and half of them don’t even know it yet, Dr. Lindenmeyer says.

It’s natural to have a lot of questions about what this means for your health and your life and what to expect next. Throughout the process, it’s important to take care of yourself and find support in people you trust.

What your hepatitis C diagnosis means

Hepatitis C is a viral infection that results in chronic inflammation of the liver. It’s spread when blood from an infected person enters the bloodstream of an uninfected person. But, it doesn’t always result in symptoms right away.

Doctors use a blood test called the hepatitis C antibody test to screen for the infection. If your results come back positive on this test, that’s not a diagnosis. That just means you’ve been exposed to the virus at some point.

A follow up test, called the hepatitis C virus RNA PCR test, can confirm whether the infection is active.

In some people, the infection goes away on its own. In other people, it progresses and scar tissue develops on the liver — a process called fibrosis.

Scarring, of course, is not good. It makes it difficult for the liver to do its many jobs, which include metabolizing proteins; filtering the blood; and breaking down, storing and releasing carbohydrates into the bloodstream.

Over time, scarring can lead to cirrhosis, liver cancer or the development of enlarged veins in the esophagus, called portal hypertension.

“Only a subset of patients will develop scarring or cirrhosis,” Dr. Lindenmeyer says. “There’s another subset of patients who will continue to have the infection but will never develop the scar tissue in their liver.”

So, what now?

If you do test positive for hepatitis C on the RNA test, a liver specialist called a hepatologist will want to learn more about the status of your infection and how much scarring is on your liver.

To do this, they will order some more blood tests that can provide insight into how well your liver is working, as well as a noninvasive ultrasound test called FibroScan® to measure scarring in the liver.

These tests are important because people who have little or no scar tissue on their liver are not going to be at risk for complications related to cirrhosis, Dr. Lindenmeyer explains. However, they will still need long-term follow-up with a hepatologist to monitor whether the disease is progressing.

On the other hand, people with cirrhosis need to be regularly screened for liver cancer and portal hypertension.

A treatment revolution

If you do need treatment for hepatitis C, your doctor will probably prescribe one or a combination of direct-acting antiviral medications. These drugs are highly effective in clearing the hepatitis C virus from the body — studies have shown they have a 98% to 99% cure rate and are generally well tolerated by people who take them.

You’ll take the medications for 8 to 24 weeks and continue to have blood tests to monitor how much of the virus is in your blood during this time.


Some other medications, including some common heartburn medicines, can interfere with these antiviral drugs, so it’s important to make sure you tell your doctor about any and all other medications you’re taking. It’s also important that your doctor has a complete medical history, as some of these medicines could potentially reactivate hepatitis B virus if you’ve been exposed to it in the past.

Life with hepatitis C

Hepatitis C is a bloodborne disease, so it’s perfectly safe to share a drink or kiss someone – you can’t spread the infection that way.

To avoid infecting someone else, it’s recommended that you take these steps:

  • Do not share toothbrushes or razors with others.
  • Do not use intravenous drugs.
  • Use barrier protection during sexual intercourse.
  • Avoid sex during menstruation.

If you have hepatitis C, it’s also important to avoid taxing the liver even more with drugs and alcohol. There is no hepatitis C-specific diet, but it’s good to maintain a healthy diet to keep your liver functioning as well as it can, Dr. Lindenmeyer says.

Once treatment is complete, your doctor will continue to monitor your viral load with blood tests. In some people, the virus relapses a few weeks after treatment ends. “But, if it hasn’t relapsed by three months, we can say confidently that the virus won’t come back,” Dr. Lindenmeyer says. At that point, you would have what’s called a sustained virological response and be considered cured.

But once you’ve been cured, it’s not a guarantee you won’t contract the virus again, Dr. Lindenmeyer notes. There are many strains and mutations of hepatitis C, so it’s important to take the following steps to avoid putting yourself at risk again:

  • Never share needles.
  • Don’t share razors or toothbrushes.
  • Take precautions to avoid direct exposure to blood if you are a healthcare worker.

Learn more about our editorial process.

Related Articles

Illustration of the herpes virus.
August 11, 2022/Cancer Care & Prevention
6 Viruses That Can Cause Cancer

It’s not just smoking and genetics that can increase your risk of cancer

Colonscopy exam showing light inside colon
March 15, 2024/Digestive
How Safe Are Colonoscopies?

They might not be fun, but colonoscopies are low-risk, high-reward procedures

Female and male waking up with hangovers in aftermath of a party
March 13, 2024/Digestive
Hangover Pills Aren’t Worth the Hype

Misleading claims, lack of scientific evidence and the risk of over-doing it are all concerns

Counter top with healthy foods and meal prepping
March 11, 2024/Digestive
Living With Celiac Disease? Make Time for Self-Care

It’s more than just avoiding gluten — it’s also important to focus on your mental and emotional health

person eating a small lunch alone at desk at the office
March 8, 2024/Digestive
How To Cope With Ulcerative Colitis at Work

Talk to your employer, ask for accommodations and manage your stress

person speaking with healthcare provider in office
March 4, 2024/Digestive
Ulcerative Colitis and Your Mental Health

Seeking help through therapy can be an important step in improving your quality of life when you have UC

Physician examines oversized colon with giant magnifying glass, with report in foreground
March 1, 2024/Digestive
Colon Cancer Screenings: When To Start

If you’re at average risk, it’s recommended that you get your first colonoscopy at age 45

Closeup of people holding up shot glasses
February 15, 2024/Digestive
What Does Alcohol Do to Your Body? 9 Ways Alcohol Affects Your Health

Alcohol affects your whole body, from your liver and immune system to your brain and mental health

Trending Topics

Person in yellow tshirt and blue jeans relaxing on green couch in living room reading texts on their phone.
Here’s How Many Calories You Naturally Burn in a Day

Your metabolism may torch 1,300 to 2,000 calories daily with no activity

woman snacking on raisins and nuts
52 Foods High In Iron

Pump up your iron intake with foods like tuna, tofu and turkey