May 16, 2023

This Is Why Your Nasal Spray Stopped Working (and What To Do About It)

‘Rebound congestion’ happens when your body starts to rely on decongestant nasal spray

nasal spray

Sniffle, sneeze, achoo! When you’re all stuffed up — whether from allergies, sinus congestion or a cold — it can sometimes be difficult to remember what it’s like to breathe through your nose. Nasal sprays can often help.


Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

But if you’ve heard that you can become addicted to nasal sprays or experience the “rebound effect,” you may be feeling a little unsure about whether it’s safe to use one of these sprays at all.

Allergist Mark Aronica, MD, explains the differences between types of nasal sprays, including which ones can become habit-forming and which ones you actually should take every day.

Is there such a thing as nasal spray addiction?

Rhinitis medicamentosa, or ‘rebound congestion,’ occurs when you overuse certain nasal sprays and your body develops a tolerance,” Dr. Aronica explains, “but it’s not quite as simple as that.”

There are a few different kinds of nasal sprays, and they should be used for different periods of time. In fact, some common types of nasal sprays used for allergy relief actually should be used daily — and those ones aren’t habit-forming.

Nasal spray types

If you have bad allergies (hay fever) or are dealing with a cold, your doctor may have suggested a nasal spray. Is it OK to take it every day? That depends on which kind you’re taking.

Daily allergy sprays aren’t habit-forming

There are a few types of nasal sprays meant to treat allergy symptoms, and they’re all slightly different (more on that in a moment). But here’s what they have in common: They’re OK to take every day. In fact, they should be taken every day if you want to truly make a dent in your allergies.

Nasal steroid sprays reduce inflammation in your nasal passages. They’re available over the counter and work best when you start taking them a few weeks before allergy season begins (whichever season that may be for you). Types include:

  • Budesonide (Rhinocort®).
  • Fluticasone (Flonase®).
  • Triamcinolone (Nasacort®).
  • Mometasone (Nasonex®).

Antihistamine sprays aren’t habit-forming, either. They include:

  • Azelastine is available over the counter as Astepro® or with a prescription as Astelin®.
  • Olopatadine (Patanase®) requires a prescription.

Saline nasal sprays moisten your nasal passages, which can flush out mucus, pollen and other irritants. They may be branded as “saline moisturizing spray” or “saline mist.”


“None of the three types of nasal sprays used for allergy symptoms — nasal steroid sprays, antihistamine sprays and saline sprays — is habit-forming,” Dr. Aronica confirms. “These sprays should be used regularly in order to alleviate allergy symptoms.”

If you’re dealing with allergies, ask your healthcare provider what kind of spray or other medication is right for you.

Decongestant nasal sprays can be habit-forming

These are the nasal sprays you might turn to when you have a cold, the flu or a sinus infection — and they’re the ones that you shouldn’t use on a regular basis. They include:

  • Oxymetazoline (Afrin®, Dristan® and Sinex).
  • Phenylephrine (Neo-Synephrine®).

“Decongestant sprays shouldn’t be used more than three or four days in a row,” Dr. Aronica states. “Any longer than that can cause you to build up a tolerance to them.”

Why? Let’s discuss.

Rebound congestion from decongestant spray overuse

You know the phrase, “Too much of a good thing”? Yeah, that’s decongestant sprays. When you use one of these sprays for more than a few days in a row, you can end up with “rebound congestion,” which is basically a vicious cycle of congestion — perpetuating your symptoms instead of relieving them.

When you’re sick and all stuffed up, decongestants narrow the blood vessels in your nose. This reduces inflammation and helps clear up your congestion, which makes you feel better. But if you use a decongestant spray for more than a few days, they start to become the problem instead of the solution.

“If you use a decongestant spray too much or too often, your body can become dependent on them,” Dr. Aronica explains. “Then, when you try to stop using the spray, your nasal passages start to swell up again, which causes your congestion to return. This can lead you to use nasal spray again in order to try to feel better.”

You see where this is going, right? It becomes a self-perpetuating cycle: You use a decongestant spray to clear up your symptoms, but if you use it too much, your body starts to rely on it — and then, your symptoms come back any time you don’t use it.


Symptoms of overuse

If your body has become dependent on a decongestant nasal spray, you won’t be able to shake those initial symptoms of congestion, like:

  • Stuffiness.
  • Sneezing.
  • Runny nose.

Importantly, though, you won’t experience other symptoms of allergies (like itchy eyes) or cold and flu (like sore throat, body aches, etc.). That’s because when you’re dealing with rebound congestion, the problem is the continued congestion itself.

How to treat nasal spray overuse

If you’ve used a decongestant nasal spray for a couple days longer than recommended, you might be able to taper off use on your own. But often, the best thing to do is speak to a healthcare professional — especially if you’ve been using a decongestant nasal spray for weeks, months or even years.

“Abruptly stopping long-term decongestant spray use can make your symptoms worse, so it’s always safest to wean off under medical supervision,” Dr. Aronica advises. “Your provider will guide you, and they can recommend other treatments or non-habit-forming medications to ease your congestion.”

How to safely use decongestant sprays

It’s important to remember that nasal spray is a medication — and like any medication, it should only be used as recommended, both in dosage (how much you use) and duration (how long you use it).

Avoid rebound congestion by following the label and not using a decongestant nasal spray for longer than the recommended amount of time (no more than five days).

“If you have prolonged congestion, it’s best to speak with your healthcare professional,” Dr. Aronica also advises. “They can help get to the root cause and recommend the right course of treatment to get you feeling better.”

Related Articles

Notes taped to window of possible new year's resolutions with hand in foreground holding marker.
December 1, 2023
How To Keep Your New Year’s Resolutions

Pick specific, measurable goals, but also be open to changing them if need be

person holding a thermometer with stress thought bubbles above head
December 1, 2023
Yes, There Is Such a Thing as Stress Sickness

From nausea, weight gain and eczema, stress can affect your immune system in many ways

bowl of soy-based cubes with hand
November 30, 2023
Can Soy Cause Breast Cancer?

Research consistently shows that soy-based foods do not increase cancer risk

person scratching neck that has eczema
November 29, 2023
How Lifestyle Changes and Self-Care Can Improve Your Atopic Dermatitis

Changing your wardrobe or environment won’t eliminate eczema, but it can help reduce flares

person stressing, with clock and books
November 29, 2023
6 Ways To Feel Less Anxious in the Mornings

Breathwork, sleep mediatation and avoiding screens can help fight back morning anxiety

covid toe
November 28, 2023
Are COVID Toes and Rashes Common Symptoms of the Coronavirus?

Chilblain-like skin lesions and rashes probably aren’t COVID related

magnesium pills out of container spelling out MG
November 28, 2023
Magnesium for Anxiety: Does It Help?

This supplement may help with regulating cortisol levels, which may help with stress

woman in her forties, using an inhaler
November 28, 2023
Why Sex Hormones Can Help (or Hurt) Your Asthma

Developmental changes like puberty and menopause can impact symptom severity

Trending Topics

group of hands holding different beverages
November 14, 2023
10 Myths About Drinking Alcohol You Should Stop Repeating

Coffee won’t cure a hangover and you definitely shouldn’t mix your cocktail with an energy drink

Person applies moisturizer as part of their skin care routine after a shower.
November 10, 2023
Korean Skin Care Routines: What You Need To Know

Focus on the philosophy — replenishing and respecting your skin — not necessarily the steps

glass of cherry juice with cherries on table
November 8, 2023
Sleepy Girl Mocktail: What’s in It and Does It Really Make You Sleep Better?

This social media sleep hack with tart cherry juice and magnesium could be worth a try