June 29, 2021/Uncategorized

What You Should Know About Kratom

A Q&A on the controversial opioid withdrawal aid

kratom plant

Kratom is one of those plants that you might assume is a safer, natural alternative to other drugs. But don’t be fooled: There’s a dark side to kratom-derived pills, powders and teas.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

In this Q&A, integrative medicine specialist Yufang Lin, MD, explains why “natural” doesn’t always mean safe, especially when it comes to kratom.

Q. What is kratom?

A. Kratom (Mitragyna speciosa) is a tree in the coffee family. It’s found in Southeast Asia and Africa. Traditionally, people have:

  • Chewed kratom leaves.
  • Made kratom tea to fight tiredness and improve productivity.
  • Used kratom as medicine.
  • Substituted kratom for opium.
  • Used kratom during religious ceremonies.

Q: What does kratom do?

A: Low doses of kratom can make you more alert. However, high doses of kratom can cause:

  • Decreased pain.
  • Pleasure.
  • Sedation.

This is because two of the compounds in kratom (mitragynine and 7-hydroxymitragynine) interact with opioid receptors in your brain.

Q: Why do people use kratom?

A: Precisely because kratom interacts with the brain’s opioid receptors, some people use it to relieve pain or overcome opioid addiction. Medical communities now try to shy away from opioid use for pain, so many patients who previously relied on them no longer can. Scrambling to find alternatives, some people turn to kratom, which is a compelling replacement because it has similar pain-relieving effects.

People tend (however incorrectly) to think that kratom is safe because it’s “natural.” It’s also legal and easily obtainable in many states — without the stigma attached to narcotics.

Q: How is kratom used?

A: Traditionally, people drink kratom as a tea or chew its leaves. Kratom can also be found in resins, extracts and tinctures.

Advertisement

These days, you may find kratom in pills, capsules, powders or even drinks. In Thailand, for example, you can buy a concoction made with kratom leaves, cough syrup, cola and ice. And kratom bars have begun to pop up across the U.S., offering kratom concoctions in place of cocktails.

Q: Does kratom have any side effects?

A: Yes. Don’t let the fact that kratom is “natural” trick you into thinking it’s safe. In fact, kratom’s potential for severe side effects outweigh its potential benefits — and in extreme cases, kratom has even caused death.

The most common side effects of kratom are:

  • Aggression.
  • Altered mental status.
  • Anxiety and irritability.
  • Constipation.
  • Delusion and hallucination.
  • Drowsiness and sedation.
  • Dry mouth.
  • Frequent urination.
  • Itching.
  • Nausea and vomiting.
  • Tongue numbness.

Other serious kratom side effects include:

  • Cardiac issues, such as heart attack, abnormal heart rhythms and high blood pressure.
  • Encephalopathy (brain disease).
  • Hallucination.
  • Hypothyroidism (underactive thyroid).
  • Insomnia.
  • Liver damage and liver failure.
  • Rhabdomyolysis (A condition that leads to kidney damage when muscles disintegrate and release a protein into the blood).
  • Respiratory depression (difficulty breathing).
  • Seizure.

Long-term kratom users may also experience:

  • Increased cheek pigmentation.
  • Loss of appetite.
  • Tremor.
  • Psychosis.
  • Weight loss.

Q. Is kratom addictive?

A: As with opioids, you can get addicted to kratom. People going through kratom withdrawal may experience:

Q: Is kratom legal?

A: The U.S. Food and Drug and Administration (FDA) has warned consumers about the dangers of using kratom. And as of mid-2021, kratom is illegal in six states:

Advertisement
  • Alabama.
  • Arkansas.
  • Indiana.
  • Rhode Island.
  • Vermont.
  • Wisconsin.

In some states, including California, Colorado, Florida and Mississippi, kratom is legal under state law but banned or controlled in some individual cities, towns and counties. In other states, various kratom legislation is still pending.

Globally, kratom is illegal or restricted in more than a dozen countries, including parts of Europe, Japan and Russia.

Q. Is kratom safe to use?

A: Due to its dangerous health effects — plus the very real risk of getting your hands on low-quality and contaminated kratom products — you should not use kratom in any form.

If you are experiencing pain or want to overcome opioid addiction, talk to your doctor. Together, you can find a safe way to reach your health goals.

Learn more about our editorial process.

Related Articles

Sad, exhausted parent holding newborn in cage surrounded by drug addiction possibilities
February 15, 2024/Children's Health
Can Babies Be Born Dependent on Drugs?

Neonatal opioid withdrawal syndrome, or NOWS, can develop when a birthing parent uses opioids, nonmedical drugs or even some prescription drugs during pregnancy

Hand holding nasel spray product with store shelves of medicine in the background.
April 17, 2023/Brain & Nervous System
Narcan Is Now FDA-Approved as an Over-the-Counter Medicine

The result is a huge win for anyone at risk of an opioid overdose

Stem Cells microscopic view
January 13, 2019/Chronic Pain
One Way to Help Patients Off of Opioids? Stem Cell Therapy Shows Promise

An innovative treatment option may be possible

acupuncture on knee
January 7, 2019/Wellness
Need Pain Relief? Try Acupuncture Instead of Opioids

New government advisory recommends non-addictive options first

test tubes filled with blood
May 4, 2022/Uncategorized
What Color Is Your Blood?

Your veins might look blue, but that’s not the color of the blood flowing inside

Two people holding hands in a comforting way
February 16, 2022/Uncategorized
What Ambiguous Loss Is and How To Deal With It

A psychologist shares ways to cope with a lack of closure

A woman with big hoop earrings and a sweater looking out a window with a pensive look on her face.
June 1, 2020/Uncategorized
Understanding (and Getting Past) the Mental Health Stigma

How to see past outdated, prevailing attitudes and views

Small white pacemaker on white and blue background
February 19, 2018/Uncategorized
Why You May Not Realize You Need a Pacemaker

Many overlook the signs of a slow heart rhythm

Trending Topics

Person in yellow tshirt and blue jeans relaxing on green couch in living room reading texts on their phone.
Here’s How Many Calories You Naturally Burn in a Day

Your metabolism may torch 1,300 to 2,000 calories daily with no activity

woman snacking on raisins and nuts
52 Foods High In Iron

Pump up your iron intake with foods like tuna, tofu and turkey

Ad