Locations:
Search IconSearch
September 20, 2019/Diet, Food & Fitness/Nutrition

What’s the Deal With Nightshade Vegetables?

Some diets shun them, but research hasn’t concluded that they’re harmful

Gardener harvesting nightshade veggies from his garden

Gluten, FODMAPs, dairy … it’s hard to keep track of what foods people are avoiding these days. And here’s another to add to the list: nightshade vegetables.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

Nightshades are a botanical family of foods and spices that contain chemical compounds called alkaloids, explains registered dietitian Ryanne Lachman. Common edible nightshades include:

  • Tomatoes.
  • Potatoes (but not sweet potatoes).
  • Eggplant.
  • Bell peppers.
  • Spices sourced from peppers, such as cayenne and paprika.

These vegetables (some of which are actually fruits) are highly nutritious diet staples in many cultures.

A single bell pepper, for example, contains well over the recommended daily amount of vitamin C, and tomatoes are a major source of the antioxidant lycopene, which some studies have associated with decreased risk of certain types of cancer.

So why do people avoid them?

Remember how nightshades contain small amounts of alkaloids? Alkaloids can be dangerous in large doses. In fact, there are many other plants in the nightshade family that are poisonous to humans (like, ahem, tobacco).

Even though they contain low levels of alkaloids, edible nightshades might, to some people, seem guilty by association. But some people also seem to think they promote inflammation — the root of many health problems.

While there haven’t been any large-scale studies demonstrating this (at least not yet), some diet plans exclude nightshades, claiming that people report feeling better when they don’t eat them.

Advertisement

But that doesn’t mean everyone should be cutting them out of their diet.

“A food sensitivity is very patient-specific and can often be a symptom of another imbalance rather than a permanent problem with that food,” Lachman says.

“If nightshades are a trigger for inflammation, it’s typically a message that there is an underlying imbalance perpetuating chronic, low levels of inflammation, and nightshades are just fuel for the fire.”

Lachman explains that if there does turn out to be any benefit in reducing nightshades, it would most likely be for those with inflammatory or autoimmune conditions like arthritis, psoriasis and possibly inflammatory bowel disease.

The takeaway

For most people, there’s no need to avoid nightshades, as studies haven’t linked them to negative health consequences. “These foods are incredibly healthy and offer more health benefits than costs,” Lachman says.

However, just like any food, it is possible to be intolerant to them. If you think you have a sensitivity to nightshades, Lachman recommends cutting them out for a few weeks while keeping a close eye on symptoms to test for tolerance.

“If avoiding nightshades improves symptoms, then we work with the patient to determine the root cause of inflammation and likely improve tolerance to nightshade foods over time,” she says.

And, in the end, if you prefer to eliminate them, it’s important to make sure you’re still getting important vitamins and antioxidants from other sources.

Lachman recommends using beets to make a “no-mato” sauce, swapping white potatoes for sweet, and using Italian spices like basil, thyme and rosemary instead of cayenne or paprika.

Advertisement

Learn more about our editorial process.

Related Articles

Arms of person bent down examining food in a bottom-of-fridge freezer bin
November 29, 2024/Nutrition
Spoiler Alert: Refrigerated Food Can Go Bad During a Power Outage

Extended outages lasting more than four hours can make food in your fridge unsafe to eat

Smiling mother looking down on baby breastfeeding
November 8, 2024/Nutrition
Intermittent Fasting While Breastfeeding: Is It Safe?

Intermittent fasting could impact your milk supply and energy levels, so it’s best to wait until you’ve weaned your baby from nursing

Adding spoonful of allulose to mug of coffee
November 4, 2024/Nutrition
What You Need To Know About Allulose

Although allulose is an FDA-approved sugar substitute, more research is needed to understand its safety

Plate of fresh kelp with seasame seeds
October 9, 2024/Nutrition
Is Kelp Good for You?

This versatile type of seaweed may help support weight loss, bone health and cancer prevention

Person in park wearing fitness apparel, drinking water from bottle, with person walking and person on bench in background
October 3, 2024/Nutrition
How Much Water You Should Drink Every Day

Consumption needs vary based on activity, weather, metabolism and other factors

A plate on table divided into balanced nutrition sizes, with fork and knife, and a spot on the table for dairy
September 27, 2024/Nutrition
What Exactly Is a Balanced Diet?

A typical recommended balanced diet is half fruits and veggies, a quarter protein and a quarter grains

Person in kitchen holding placard with six foods containing calcium, like tofu, broccoli and almonds
September 6, 2024/Nutrition
Food for Your Bones: How To Follow the Osteoporosis Diet

Eating enough dairy, fish and leafy greens is a good way to help keep your bones strong

Tofu and vegetables in enamel serving skillet
August 27, 2024/Nutrition
What You Need To Know About the Ornish Diet

This low-fat, plant-based eating plan includes lifestyle changes, such as exercise, stress management and social support

Trending Topics

Person touching aching ear, with home remedies floating around
Home Remedies for an Ear Infection: What To Try and What To Avoid

Not all ear infections need antibiotics — cold and warm compresses and changing up your sleep position can help

Infographic of foods high in iron, including shrimp, oysters, peas, cream of wheat, prunes, eggs, broccoli, beef and chicken
52 Foods High In Iron

Pump up your iron intake with foods like tuna, tofu and turkey

Person squeezing half a lemon into a glass of water
Is Starting Your Day With Lemon Water Healthy?

A glass of lemon water in the morning can help with digestion and boost vitamin C levels, and may even help get you into a better routine

Ad