Locations:
Search IconSearch

How Good Bacteria in Your Nose Fights Infections

Reduce unnecessary antibiotics to help your immune system

woman sneezing wiping nose

The “good bacteria” in our gastrointestinal tracts has gotten a lot of attention lately, but our guts aren’t the only places that host good bacteria. Our noses, sinuses and nasal passages contain similar colonies of beneficial bacteria.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

The bacteria in these areas are starting to move into the spotlight as more research is done on the positive impacts those bacteria can have in preventing the bad bacteria from colonizing and the negative impacts that result when we destroy the good bacteria.

“There are a lot of bacteria that colonize our nose and throat that are supposed to be there,” says head and neck specialist Michael Benninger, MD. “But primarily due to overuse of antibiotics, we have changed the colonies in our nose to bacteria that are more harmful.”

Among these are bacteria that lead to some of the common staph, streptococcus pneumonia, H-flu, sinusitis and strep throat infections that regularly plague people, he adds.

How to make sure you have good bacteria in your body

Preserving the good bacteria starts with a more conservative use of antibiotics. That means physicians are now less likely to prescribe antibiotics to treat infections that don’t always warrant their use.

“The principles of sinus therapy, particularly since many people were being treated for viruses where antibiotics aren’t helpful anyway, are to avoid antibiotic use, unless it is very clear that it is a bacterial infection,” explains Dr. Benninger. “That will allow our normal bacteria to recolonize our nose, nasopharynx and throat so they can fight infections naturally.”

Advertisement

How to prevent nose infections

Right now, the best steps you can take are related to prevention of infections, including the following:

  • Work with your doctor to determine whether or not you have a bacterial infection. “We shouldn’t treat infections with an antibiotic until 10 to 14 days after the onset,” Dr. Benninger says. “If it’s viral, it will be self-limited and will run its course, so if you treat it with an antibiotic, it just increases the likelihood of colonizing bad bacteria by killing the good bacteria with the antibiotics.”
  • Wash out the bad stuff yourself. Use saline irrigation products like a neti pot to clear out some of the bad bacteria and fungus in your nose that can cause inflammation.
  • Use over-the-counter treatments to relieve the symptoms. Taken at the onset of symptoms, products such as Nasacort®, an intranasal steroid, which are mostly over-the-counter, such as triamcinolone acetonide, fluticasone propionate or budesonide, will help reduce inflammation and mucus production and can shorten the course of the viral infection. Nasal decongestants like oxymetazoline (Afrin®) can help you breathe better.
  • Keep your hands clean. Wash your hands or use a hand cleanser. Keep your hands away from your eyes, nose and mouth.
  • Take long-term preventive steps to avoid getting these infections. Do aerobic exercises and get plenty of rest and proper hydration. People who do aerobic exercise on a routine basis strengthen their immune system. This makes them a third less likely to get a cold, virus or bacterial sinusitis in the first place.

The future health of our noses

Like gut flora, good nasal flora will eventually have probiotics to help nourish and cultivate them. Some of these products are already in use in Europe. However, they have not yet been approved in the United States because of the more stringent FDA regulations.

“Right now, we’re in preventive mode,” Dr. Benninger says. “But in the future, we will likely be using probiotics in the nose and sinuses, similar to what we do in the GI tract.”

Advertisement

Cleveland Clinic icon
Health Essentials logo
Subscription icon

Better health starts here

Sign up for our Health Essentials emails for expert guidance on nutrition, fitness, sleep, skin care and more.

Learn more about our editorial process.

Related Articles

man with long nose hairs
May 3, 2022/Ear, Nose & Throat

Why Nose Hairs Grow So Long

How to handle the thicket of long hairs sprouting from your nose

Hand pumping liquid soap from bottle onto other hand
June 2, 2026/Primary Care

Should You Be Using Antibacterial Soap or Regular Soap?

Antibacterial soap hasn’t been shown to be any more effective at killing germs than regular soap and water

Healthcare provider adjusting IV fluid, with patient nearby
June 1, 2026/Skin Care & Beauty

When a GPP Flare Needs Urgent Care

Signs like fever, breathing problems and muscle weakness, along with red patches and pus-filled bumps, mean it’s time for emergency treatment

Wallet, credit cards, change and money laid out
May 29, 2026/Infectious Disease

How Dirty Is Your Money? And Should You Be Washing It?

Your dollar bills, coins and cards are covered in germs — but they’re very unlikely to make you sick

Person sitting on couch, head in hand, hand on stomach, doubled over

4 Early Signs That May Signal a Systemic Mastocytosis Flare

Some flares begin with subtle changes, like flushing, agitation or a strange metallic taste, before more serious symptoms appear

Different kinds of healthcare providers and patient with blood disorder

Who Should Be on Your Care Team for Systemic Mastocytosis?

A hematologist-oncologist, an allergist/immunologist and a primary care provider will likely all be key players

Person shrugging surrounded by environmental triggers

Tips for Avoiding Environmental Triggers of Systemic Mastocytosis

Everyday exposures, like fragrances, cleaning supplies and pollen, can trigger symptoms

Kids playing tag outside
May 21, 2026/Infectious Disease

What We Can Learn From a Case of the Cooties

The imaginary illness that routinely spreads on playgrounds offers some real-life lessons

Trending Topics

Person lying on couch, arms wrapped tightly around their stomach, grimacing

How To Avoid Getting Norovirus

The virus that causes the so-called ‘stomach flu’ can cling to surfaces for days or even weeks

Palm with two capsules on it

How Melatonin Impacts Heart Health

There isn’t clear evidence that melatonin harms your heart — but finding the cause of sleep issues is key to long-term heart health

Wallet, credit cards, change and money laid out

How Dirty Is Your Money? And Should You Be Washing It?

Your dollar bills, coins and cards are covered in germs — but they’re very unlikely to make you sick

Ad