The common flavor enhancer has had a bad reputation — but here’s what the research shows
Monosodium glutamate, or MSG, is one of the most popular flavor enhancers in the world — an ingredient that gives food a savory or umami taste. Made from an amino acid called L-glutamic acid, it’s produced by fermenting corn, sugar cane, sugar beets, tapioca or molasses.
Advertisement
Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy
In the late 1960s, MSG came under fire for allegedly being a toxic addition to some favorite foods, from soups and salad dressings to Chinese takeout and French fries.
Since then, research has debunked the myth that MSG is a villainous ingredient, and research shows that in small amounts, it doesn’t cause any significant or lasting harm.
In the past, MSG has been linked to having negative effects on:
Most of those myths around MSG have been dispelled, and the U.S. Food and Drug Administration (FDA) says MSG is “generally recognized as safe.” Global food-regulating bodies like the United Nations Food and Agriculture Organization (FAO) agree.
Still, MSG continues to be a controversial ingredient, in part due to a longstanding stigma and a lack of conclusive data about it, says registered dietitian Beth Czerwony, RD, LD.
For example, there’s confusion around MSG’s association with higher rates of obesity. MSG has not been shown to affect fat cells, leptin receptors or other parts of the body associated with weight gain, but some research still shows that higher MSG intake is related to a higher body mass index (BMI) over time.
Advertisement
Still, studies on the topic show conflicting results. So, right now, there’s no certain proof of how MSG and obesity are linked.
One explanation for the ingredient’s possible link to obesity, Czerwony says, is that MSG makes our food taste better.
“When your food tastes better, you’re likely to eat more of it,” she poses.
If you’ve ever heard someone talk about having “an MSG attack,” they’re referring to experiencing a group of symptoms sometimes said to occur after consuming MSG.
Symptoms may include:
This sensitivity is sometimes called “MSG symptom complex,” but research shows that it only affects a very small percentage of people who are sensitive to MSG — and even then, these effects are short-term and should disappear in less than an hour.
What’s more, the FDA says these MSG side effects are most likely to occur after a person with MSG sensitivity has consumed 3 grams or more of MSG on its own without food. That, in itself, is pretty unlikely, given that most people consume MSG in food, and most food contains less than 0.5 grams of added MSG.
In other words? MSG is still generally thought to be safe in moderation — and most foods with MSG in them only have a very small amount.
Sometimes, Czerwony recognizes, a bias against MSG leads people to assume they’re having a reaction to MSG, which can prevent them from identifying the real culprit.
“Your symptoms might be from something else in the food,” she says. “There’s MSG in fast food, snack foods, seasoning blends, instant noodles, frozen meals — all foods that are highly processed and can cause issues like flushing, headaches or a change in blood pressure from your body’s response to high salt content and other ingredients.”
So, it may very well not be the MSG that’s making you feel ill, but the fact that you’re eating foods that are already highly processed, fried, full of sodium, etc.
This flavor enhancer gives an umami kick to many popular Asian dishes, and it’s often added to fast food items like fried chicken.
Umami foods increase saliva production — literally, they make your mouth water — which improves the way food tastes. And although MSG does add a salty flavor to foods, it has just one-third the amount of sodium as standard table salt, which makes it a popular substitution.
Though it naturally occurs in tomatoes, cheeses and some other foods, MSG is also commonly added to processed food items, like:
Advertisement
“MSG is one of the most widely used food additives, and it’s in a lot more foods than people think,” Czerwony shares. “It’s most commonly thought of as being in Chinese food, but it’s in a lot of other things as well.”
The FDA requires MSG to be listed on the labels of processed foods that include it. But processed foods that include ingredients with naturally occurring MSG don’t have to specify that they include added MSG.
If a processed food includes one of these naturally occurring ingredients, it contains MSG:
While research hasn’t found MSG to directly cause obesity or other medical conditions, if you’re worried about MSG in the foods you eat, Czerwony has some advice.
“Just do your best to read your food labels,” she says, “and if you go out to eat, you can ask to have the MSG left out of your dish. Just know, though, that without it, your meal may not have the same umami taste you’d otherwise expect.”
If you experience negative side effects when you consume foods that have MSG, you may want to avoid it. But most people can rest easy knowing that MSG isn’t the toxic ingredient it was once purported to be. There’s no reason to avoid small amounts of MSG in your diet — so go ahead, enjoy that stir-fry worry-free.
Advertisement
Learn more about our editorial process.
Advertisement
This herbal drink may ease allergies and boost prostate health
This ancient grain, packed with protein and fiber, can help with weight loss and heart health
From protecting against cellular damage to helping prevent kidney stones, lemons are as healthy as they are tangy
This leafy green can aid weight loss, boost eye health and help prevent cancer
It depends on factors like your age, activity level and if you want to maintain, lose or gain weight
It’s hard to beat the benefits of oats, but be cautious of sugared-up instant oatmeal options
They may not be your favorite veggie, but they’re packed with disease-fighting nutrients and tasty when roasted
Mineral-rich seaweed is good for your heart, digestion, muscles and more
If you’re feeling short of breath, sleep can be tough — propping yourself up or sleeping on your side may help
If you fear the unknown or find yourself needing reassurance often, you may identify with this attachment style
If you’re looking to boost your gut health, it’s better to get fiber from whole foods