Locations:
Search IconSearch
February 6, 2020/Health Conditions/Allergies

Allergy Tests: Now You Can Find Out if You’re Allergic to a Male or Female Dog

An advanced blood test is changing the allergy game

Woman allergic to dog being held by man

Dog allergies are pretty common. People who have allergic reactions to dogs are usually reacting to the pet’s dander, which is made up of secreted proteins from dead skins cells, saliva or urine. (Yuck!)

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

Eventually these proteins make their way to the pet’s fur, or it could settle on your clothes, couches and carpets.

If you’re allergic to dogs, you might find yourself suddenly itching, coughing or wheezing when there’s one around. But what if you could better narrow down the dog you’re allergic to?

Is your friend’s female pug causing your sneezing attacks? Or is it the male Labrador retriever that’s triggering your allergy misery?

Now, there’s a precise allergy test ― called an in vitro allergen test ― that gives you details about whether you’re allergic to a female or male dog.

How the allergy test works

Ear, nose and throat specialist Michael Benninger, MD, says it’s sometimes hard to know if your allergic reaction is to furry animals in general, or if it’s to one very specific animal. The test can help identify what animal might be triggering your allergy attack.

This innovative test gives you much more information, unlike a skin test that may tell you that you’re allergic to cats and dogs when you’re actually, in fact, only allergic to one of them. It can assess your sensitivity to distinct types of furry animals, including dogs, cats and even horses.

The test can also pinpoint the exact protein that triggers your allergic reaction ― and from what animal or animals. And if you’re allergic to a male dog or female dog.

Advertisement

How is that possible? Dr. Benninger explains that about 40% of people who test positive for dog allergies are only allergic to prostate protein. And since only male dogs (obviously) have prostates, if everything else is negative, the person can be near a female dog and not have any sort of allergic reaction.

That means you can know which dogs to avoid. Or (yes!) which one you can adopt for your very own.

As of right now, testing for either male or female components is only available for dog allergies. But Dr. Benninger says the test is changing the game for allergies and helping to improve the quality of life for those that suffer from them.

Other uses for this type of allergy testing

This type of component allergy testing is quickly breaking new ground in common animal and food allergies involving proteins.

These specific protein tests can help to refine the major culprits in people who have multiple allergies where there may be overlap in traditional allergy tests, so that allergy avoidance can be maximized and treatment individualized.

The same test can also help determine serious, life-threatening reactions in those who have peanut allergies.

For example, about 77% of those who are allergic to peanuts are not at risk for anaphylaxis (a severe response including swelling, hives, lowered blood pressure and sometimes shock). This could help some of those PB&J lovers who don’t really have to avoid peanuts altogether.

Advertisement

Learn more about our editorial process.

Related Articles

Person sitting on couch at night, pressing their hands on their nose/sinuses
April 4, 2025/Allergies
Why Your Allergies May Be Worse at Night — and What To Do About It

If allergies have you coughing and sniffling all night, try showering before bed, keeping the windows closed and propping your head up

Person outside house, holding scratchy, sore throat
April 3, 2025/Allergies
Why Your Allergies Are Worse in the Morning

If allergies make your mornings a slog, consider closing the windows and showering at night

Arms of person standing outside, scratching a dotted red rash on arm
October 1, 2024/Allergies
Things You May Not Know You Could Be Allergic To

Water, touch, sunlight, physical activity and cold are some of the rarest allergies

female on couch, holding mug, under blanket, blowing nose, cat on couch
January 22, 2024/Allergies
Why Are My Allergies Acting Up in Winter?

Indoor allergens know no season!

person blowing their nose outside
May 17, 2023/Allergies
Allergies Don’t Cause a Fever — At Least, Not Directly

Infections like sinusitis, colds, flu and COVID-19 can cause a fever, but allergies aren’t infections

Graphic of a woman blowing her nose.
March 14, 2023/Allergies
Allergy Season Is Here To Stay

Every season comes with its own set of allergens

Doctor preparing to administer shot.
January 20, 2023/Allergies
How To Minimize Your Reaction to Allergy Shots

Although allergic reactions are usually mild, taking your meds and avoiding exercise can help

hyperallergenic pillow mattress cover
January 3, 2023/Allergies
Does Hypoallergenic Bedding Work?

It can help reduce exposure to allergens, but don't expect it to solve allergy or asthma issues

Trending Topics

Person in bed sleeping on their side, covers off
Breathing Problems? Try These Sleep Positions

If you’re feeling short of breath, sleep can be tough — propping yourself up or sleeping on your side may help

A couple looking at skyline, with one person slightly behind the other, head bent down
What Is Anxious Attachment Style — and Do You Have It?

If you fear the unknown or find yourself needing reassurance often, you may identify with this attachment style

Glasses and bottle of yellow-colored prebiotic soda, with mint, lemon and ginger garnish
Are Prebiotic Sodas Good for You?

If you’re looking to boost your gut health, it’s better to get fiber from whole foods

Ad