July 5, 2022/Nutrition

How Saffron Could Benefit Your Health

7 health benefits of this colorful, antioxidant-rich spice

close-up of saffron

Saffron adds a lovely color to your food. Could it add a big boost to your health as well? Registered dietitian Beth Czerwony, RD, dives into the science behind saffron and explains how to use the spice safely.


Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

What is saffron?

Saffron, a spice that originated in Asia, has a long history as a healing or health-boosting plant. Also known as Crocus sativus L., people have used saffron as a flavoring, coloring agent and health remedy for thousands of years.

Czerwony explains recent research on this reddish flower, sharing how saffron could have several health benefits.

Health benefits of saffron

Many studies — most of them small — suggest that saffron could boost your health or help with specific health issues. That research shows saffron could hold promise as a:

1. Antioxidant boost

Saffron, like many other herbs and plants, is rich in antioxidants. These substances help fight cell damage and may prevent cancer or other diseases. Research has also shown that the antioxidants in saffron may be healthy for your brain and nervous system.

Crocetin, crocin and safranal, three antioxidants found in saffron, may help improve memory and learning ability. These substances may also help prevent neurological conditions like Parkinson’s disease.

“The antioxidants in saffron could help protect the brain from damage,” says Czerwony. “Antioxidants are beneficial substances, and you should get them from a variety of sources. Eating a diet rich in fruits and vegetables is a powerful way to boost your antioxidant intake and prevent disease. Add some saffron to a healthy diet to increase your antioxidants.”

2. PMS reliever

Premenstrual syndrome (PMS) can cause a variety of symptoms, from pelvic pain to acne breakouts. For many people, PMS impacts their mental health, causing anxiety, depression and mood swings. Some small research studies have found that saffron could improve PMS-related depression.

“Premenstrual syndrome can negatively affect a person’s quality of life,” says Czerwony. “If you experience PMS that is severe or interfering with your daily activities, talk to your provider. Saffron could also help relieve some of the emotional symptoms of PMS.”


3. Weight loss aid

Losing weight can be hard, especially when your appetite seems to be working against you. One study on a group of women found that taking saffron helped them feel less hungry and snack less frequently.

“Some evidence shows saffron can suppress your appetite and help you lose weight,” says Czerwony. “But it doesn’t work alone. Combine saffron with a healthy, balanced diet for success.”

4. Seizure treatment

Saffron is used as an anticonvulsant (anti-seizure) remedy in Iranian folk medicine. Some studies in biologic models show that it can shorten some types of seizures. However, says Czerwony, we need larger clinical trials to find out more about how it works.

“Saffron could hold promise as a seizure treatment, but we need more data about its safety and effectiveness,” notes Czerwony. “If you have a seizure disorder, ask your provider before taking herbs or supplements like saffron.”

5. ED remedy

Erectile dysfunction (ED), the ability to maintain an erection, affects millions. And saffron could be a treatment for ED, according to some research.

“Providers often recommend ED medication, which works for many people,” says Czerwony. “But those looking for an herbal remedy could try saffron. Studies found 30 milligrams a day to be effective, but don’t exceed this amount. High amounts of saffron can be toxic.”

6. Alzheimer’s disease treatment

Saffron could be as effective as a prescription medication for treating mild to moderate Alzheimer’s disease. There isn’t a cure for Alzheimer’s, but studies suggest saffron could help slow its progression and relieve symptoms.

Some small studies found that saffron extract improved cognitive function in people with mild to moderate Alzheimer’s,” says Czerwony. “Saffron also has a low risk of side effects. People with Alzheimer’s disease should see their provider regularly and discuss any supplements they take.”


7. Depression treatment

Depression is a mental health disorder affecting millions of people worldwide. Treatment may involve different types of therapy or medications. Some studies show that consuming saffron could help with symptoms of depression.

“Saffron could become a future depression treatment if we get more evidence and data,” says Czerwony. “However, we need larger studies that look at long-term outcomes before saffron can replace proven depression medications. Don’t stop taking any of your prescription medications without talking with your provider.”

How to use saffron

Saffron flower petals look like thin, red threads. Soak a few threads in hot water to make saffron tea, or mix the liquid into savory dishes for flavor. And be prepared for the price — it’s one of the most expensive spices in the world.

You can also purchase saffron capsules to swallow if you don’t like the flavor. But before taking any supplements, ask your healthcare provider if it’s safe for you. Some supplements can have unwanted side effects, especially if you’re pregnant, taking medications or have any health conditions.

“Saffron is usually safe when people use small amounts in cooking or as a tea,” says Czerwony. “It’s also packed with antioxidants, so we know it has health benefits. Before taking saffron, however, check with your provider to be sure it’s safe for you.”

Learn more about our editorial process.

Related Articles

Variety of foods that contain the antioxidant lutein
April 4, 2024/Nutrition
What Is Lutein? Learn About Its Health Benefits

This powerful carotenoid can help with your eye and skin health, LDL reduction and cognitive function

Assorted fruits and vegetables in variety of colors
March 27, 2024/Nutrition
What Is Zeaxanthin? Benefits and Side Effects

Found in colorful foods like spinach, corn and oranges, this carotenoid helps with eye, skin and liver health

Colorful fruit, vegetables and nuts combined in bowl and scattered on table
March 15, 2024/Nutrition
Phytonutrients: What They Are and Where To Find Them

These typically colorful plant-based substances provide various health benefits that help protect you from disease

assorted vessels of olive oil on a wooden table with olives in spoon
January 16, 2024/Nutrition
6 Major Benefits of Extra Virgin Olive Oil

EVOO is full of antioxidants and has anti-inflammatory properties, both of which aid your body in multiple ways

Tamarind pods displayed on brown plate on a wooden table, with one pod torn open showing fruit inside.
May 8, 2023/Nutrition
Why Tamarind Just Might Be Your New Favorite Fruit

With a sweet, tangy flavor, tamarind is super versatile and high in antioxidants

strawberries, blueberries, blackberries and raspberries
April 30, 2023/Nutrition
What You Need To Know About Flavonoids

These bright and vibrant plant compounds can benefit your health in many ways

An older person holds both hands out in front of them and squeezes each one as if to relieve tension.
July 18, 2022/Wellness
Why You Should Care About Free Radicals

When free radicals don’t have antioxidants to keep them in check, they go rogue

Close up photo of a person holding three orange pills in their hand
March 27, 2022/Diet, Food & Fitness
What Is CoQ10?

Learn about this powerful antioxidant that you can also take as a supplement

Trending Topics

Person in yellow tshirt and blue jeans relaxing on green couch in living room reading texts on their phone.
Here’s How Many Calories You Naturally Burn in a Day

Your metabolism may torch 1,300 to 2,000 calories daily with no activity

woman snacking on raisins and nuts
52 Foods High In Iron

Pump up your iron intake with foods like tuna, tofu and turkey