Locations:
Search IconSearch

How Do You Know if Your Newborn’s Jaundice Is Serious?

Jaundice that’s present at birth or lasts more than a week should be evaluated by a pediatrician

Newborn baby being treated with blue UV light for jaundice

Noticing that your newborn baby’s skin and eyes are tinged yellow can easily send parents into panic mode, especially if you’ve never seen it before.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

This yellow discoloration is called jaundice, and in newborns, it typically sets in on the second or third day after birth. It’s a common issue that usually goes away on its own, says pediatric gastroenterologist Kadakkal Radhakrishnan, MD — but sometimes, it signifies a larger health issue.

Understanding newborn jaundice

Jaundice in newborns happens when a yellowish pigment called bilirubin builds up in their blood. Our bodies make bilirubin as they break down excess red blood cells and send it through the blood and into the liver to be processed.

“After birth, when your new baby begins breathing, the extra red blood cells they had in the uterus start breaking down,” Dr. Radhakrishnan explains. “This generates a higher level of bilirubin in all babies within a few days of birth.”

Plus, newborns’ livers aren’t always well-developed enough to process bilirubin. This causes a buildup of bilirubin, which gives a yellow hue to a baby’s face and the whites of their eyes. In babies with darker skin, this yellowing may be less noticeable in their skin and more obvious in their eyes.

Jaundice may be worse in babies who:

When jaundice is normal

Most newborns develop some degree of jaundice a few days after they’re born. Usually, it goes away on its own — no treatment needed.

Advertisement

At your baby’s first doctor’s appointment (which usually happens three to five days after they’re born), their pediatrician will evaluate their jaundice level and address any concerns.

“It’s normal for parents to worry about jaundice at first,” Dr. Radhakrishnan acknowledges, “but often, it’s nothing to be concerned about.”

When jaundice requires medical attention

Jaundice usually improves on its own and doesn’t require treatment. But if it sticks around for longer than a week, it needs to be re-evaluated by your child’s doctor.

Contact your pediatrician if your baby’s jaundice:

  • Doesn’t fade within a week of birth
  • Starts to look more yellow at any time after birth
  • Spreads to their chest and/or belly

After re-checking your baby’s bilirubin level, their pediatrician will decide whether and how to treat their jaundice. The most common treatment is phototherapy, which uses blue lights to help your baby’s liver process extra bilirubin. Babies born preterm may need more aggressive treatment than babies born at full term.

“Often, elevated bilirubin doesn’t lead to any major health problems,” Dr. Radhakrishnan says. “But very high levels, or untreated high levels, may cause brain damage, and the risk is higher for preterm babies.”

If their jaundice persists, their doctor will consider liver-related conditions that affect the flow of digestive fluid (bile) to the intestine. These problems aren’t common, but it’s important to talk to your baby’s doctor if you notice long-lasting jaundice.

What if your baby is born with jaundice?

If your baby has yellowish skin and eyes as soon as they’re born — or if it sets in very quickly in their first 24 hours of life — it could be something more than standard jaundice.

Jaundice present at birth may be caused by an underlying medical issue, like:

  • A blood infection (sepsis)
  • Certain viral infections
  • A blood disorder that causes hemolytic anemia
  • Your baby’s blood type being incompatible with yours

If your baby’s jaundice is noticeable on the first day of their life, it will be evaluated while they’re still in the hospital. If you’ve given birth outside of a hospital, it’s important to be sure they’re seen by a healthcare provider right away.

A final word about babies and jaundice

Eating well can help resolve regular jaundice in newborns.

“This helps them have good bowel movements, which makes sure bilirubin gets excreted through their intestine,” Dr. Radhakrishnan explains. “For this reason, your child’s doctor may advise supplementary formula feeding beyond breastfeeding sometimes, if indicated.”

If you have concerns about jaundice, feeding or anything else related to your newborn’s health, don’t hesitate to contact your pediatrician.

Advertisement

Cleveland Clinic icon
Health Essentials logo
Subscription icon

Better health starts here

Sign up for our Health Essentials emails for expert guidance on nutrition, fitness, sleep, skin care and more.

Learn more about our editorial process.

Related Articles

Healthcare provider with stethoscope on toddler's back, listening to their lungs
March 6, 2026/Children’s Health

Croup vs. RSV: How To Tell the Difference

Both respiratory illnesses cause coughing, but croup brings a distinctive ‘barking’ sound

Baby on their belly, holding teething ring up to their mouth
February 25, 2026/Children’s Health

Teething Doesn’t Cause Fevers — and Other Myths To Sink Your Teeth Into

Most teething symptoms are mild — fevers and other major symptoms are likely something else

Caregiver giving newborn a bath, gently removing cradle cap with comb
February 9, 2026/Children’s Health

How To Get Rid of Cradle Cap at Home

Gentle care, like moisturizing, washing and soft brushing, can help clear up cradle cap

Healthcare provider giving newborn a shot in their tiny thigh
January 29, 2026/Children’s Health

How the Vitamin K Injection Protects Your Newborn

Babies are born with very little of this vitamin, which plays a critical role in the blood clotting process

Adult palms of hands with symptoms of hand, foot and mouth disease
January 28, 2026/Infectious Disease

Can Adults Get Hand, Foot and Mouth Disease?

Yes, but symptoms can be easy to miss

Caregiver holding a thermometer, comforting sick child wrapped in blanket on couch
November 17, 2025/Children’s Health

ER vs. Urgent Care vs. Pediatrician: How To Know Where To Go When Your Child Is Hurt or Sick

The emergency room is for serious medical issues; urgent care can help when you can’t get a quick appointment with your child’s doctor

Parent doing bicycle legs on their fussy baby
November 10, 2025/Children’s Health

Why Gripe Water Isn’t the Best Answer for Your Fussy, Gassy or Colicky Baby

Gripe water isn’t regulated by the FDA, and research doesn’t support its use

Hands combing wet hair with head lice comb
October 13, 2025/Skin Care & Beauty

Do Lice Jump? And Other Must-Know Facts

Lice don’t jump — but they can spread with direct head contact

Trending Topics

Peson sitting at table with laptop, elbows on table and hands at their temples

How To Get Past ‘Analysis Paralysis’

Simplifying choices, a reassuring attitude and avoiding information overload can help you overcome indecision

Person holding their nose in a smelly home

Is Thirdhand Smoke a Hidden Health Risk?

Nicotine and other lingering chemicals from smoking can harm people who don’t smoke, including children

Bottles of essential oils alongside plants

Essential Oils and Allergies: What the Science Says

The research is mixed, but experts agree: The risks outweigh the benefits

Ad