Locations:

Should You Add Collagen Supplements to Your Skin Care Routine?

Though popular with influencers and celebrities, there’s little research to back up claims that they work

Woman looking in mirror and pulling skin until wrinkles disappear

Has this happened to you? When you look in the mirror, you’ve started to notice wrinkles or sagging skin in your reflection.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

So, what gives? Could collagen loss be the culprit for your less-than-stellar appearance?

“Collagen is the main structural protein in our skin. It helps the dermis retain its firmness and elasticity. It’s also found elsewhere, like in our bones, tendons and cartilage,” explains dermatologist Shilpi Khetarpal, MD.

“At some point in our 20s, we all start experiencing a steady, gradual decline of our natural collagen ― just how much and how fast depends largely on factors like sun exposure, smoking cigarettes and air quality. As we lose collagen, our skin becomes drier and more wrinkled.”

So, what can you do? Should you start taking collagen supplements?

Collagen supplements — which have been touted by social media influencers and celebrities — come in different forms: powder, capsules or gummies.

But you may want to think twice before you start working collagen supplements into your daily routine.

Dr. Khetarpal explains whether you’ll see a difference from using collagen supplements and offers up some other ways to keep your skin in its best shape.

Learn the potential benefits of collagen supplements.

Do collagen supplements work?

Collagen supplements aren’t the best option if you want to improve the appearance of your skin. That’s mainly because there’s no evidence-based science to prove they work — or that they’re safe.

Advertisement

“A few small studies have shown limited improvement in skin texture with collagen supplements,” notes Dr. Khetarpal. “But it’s important to point out that they’re all manufacturer-sponsored studies. And unfortunately, the supplement industry isn’t well regulated and has a history of inaccurate labeling and contamination.”

You may be curious about why collagen supplements don’t work. Dr. Khetarpal says that collagen supplements are mostly absorbed by your GI tract, which means that there isn’t enough collagen that makes it into your bloodstream to be delivered to your hair, nails and skin.

Another factor? Most supplements are made with animal collagen and it’s unclear whether this form of collagen is close enough to human collagen to be beneficial.

Potential collagen supplements benefits

Fans of collagen supplements claim that they may:

But remember: Research doesn’t necessarily back up the benefits of collagen supplements.

So, how long would it take for collagen supplements to work?

You’ll need to manage your expectations if you choose to try collagen supplements. It can take three to six months of use before you may begin to see results.

Are collagen supplements safe?

The processed form of collagen, which may be called collagen peptides, comes from animal tissue discarded by meat processors. This substance is ground into a gelatin or powder and placed in a capsule or gummy tablet, along with other sometimes-unnamed byproducts. With the increasing number of food allergies today, this is a critical consideration.

Collagen supplement side effects

Should you watch for any side effects if you decide to take collagen supplements?

Overall, the side effects of collagen supplements are minimal. You may experience the following:

  • Headache
  • Lightheadedness
  • Diarrhea

How to take these supplements

There are countless brands and options of collagen supplements available. If you want to try collagen supplements, you should follow the manufacturer’s directions. A daily dose may be anywhere from 2.5 to 15 grams.

If you’re using collagen powder, you can add it to your protein shakes, coffee and even smoothies.

You may want to also consider the cost of collagen supplements — especially if you take them daily. It can be a costly endeavor that may not add up to any meaningful results.

Bottom line?

Collagen supplements may not be the best line of defense in keeping your skin looking its best. But Dr. Khetarpal says there are other options out there.

Advertisement

You may want to consider procedures ― like microneedling ― which are performed by board-certified dermatologists to stimulate collagen. Your dermatologist may also suggest vitamin A-based topicals, such as tretinoin (Refissa®, Renova® and Retin-A®), which have shown in scientific studies and extended practice to be effective.

And most importantly? There are small things you can do each day to protect your skin.

“If we want to slow down the loss of collagen, it’s best to know and avoid environmental hazards. Specifically, stay away from cigarettes and other harmful toxins, consistently apply sunscreen and wear hats and other protective clothing when outdoors,” advises Dr. Khetarpal.

“It’s also helpful to use topical antioxidants (like vitamins C and E) to protect against external aggressors like smoke and UV rays. Lastly, it’s very important to stay well-hydrated. That means drinking at least 64 ounces of fluids every day.”

Advertisement

Cleveland Clinic icon
Health Essentials logo
Subscription icon

Better health starts here

Sign up for our Health Essentials emails for expert guidance on nutrition, fitness, sleep, skin care and more.

Learn more about our editorial process.

Health Library
Collagen

Related Articles

Person spraying skin care product on their face
August 7, 2026/Skin Care & Beauty

Hypochlorous Acid: A Gentle Cleanser That Fights Bacteria

This multitasker can help keep your skin clear, support wound healing and disinfect surfaces around your home

Person using micellar water to remove make-up
August 7, 2026/Skin Care & Beauty

Micellar Water: What It Is and How To Use It in Your Skin Care Routine

This gentle facial cleanser removes dirt, oil and most makeup without drying out your skin

Person lying in tanning bed, closing it
July 2, 2026/Skin Care & Beauty

Unhealthy Glow: The Dangers of Tanning Beds

UVA rays from tanning beds increase your risk of skin cancer, wrinkles and eye damage

Person applying olive oil on hand to get glue off skin
June 4, 2026/Skin Care & Beauty

Sticky Situation: How To Get Super Glue Off Your Skin

Warm water, lotion, cooking oils or nail polish remover may all help to loosen the adhesive

Caregiver applying makeup to smiling teen
March 31, 2026/Children’s Health

Is It OK for Your Kid To Wear Makeup? 5 Things To Consider

Educate your child about body image, expectations and skin care first

Hands mixing ground coffee beans and lotion for a face mask
March 18, 2026/Skin Care & Beauty

Is Coffee Good for Your Skin?

Coffee skin care products contain anti-aging and brightening benefits — but there may be better options

Beef tallow in jar on counter, with spatula
February 10, 2026/Skin Care & Beauty

Beef Tallow for Skin: Is It Useful?

Although it could be used as a moisturizer, this new trend is not recommended

Veggies in strainer in sink with water running, with bottle of hydrogen peroxide and mixing bowl on counter
January 16, 2026/Skin Care & Beauty

Hydrogen Peroxide: When To Use It and When To Skip It

It’s a great disinfectant for around your home, but not for your skin

Trending Topics

Person looking at face in mirror, seeing changes in their skin

How Taking a GLP-1 Medication Can Affect Your Face, Body and Overall Appearance

Rapid weight loss can cause loose skin, facial volume loss and body contour changes

Person sitting in chair with hand on tummy and hand on mouth, burping

Burping a Lot? These Could Be the Reasons Why

Swallowing too much air, certain foods and drinks, and digestive conditions can all make you belch more

People practicing safe hygiene to ward off sickness, like washing hands and disinfecting

Why Is Everybody Getting Sick?

From poor hand hygiene and ventilation issues to contaminated food, many factors can make infectious diseases spread quickly

Ad