Locations:
Search IconSearch

What’s Best for Dandruff That Won’t Go Away?

The short answer from a dermatologist

Dandruff in hair
Learn three effective ways to manage dandruff.

Q: What do you recommend for resistant dandruff?

A: Skin or scalp dandruff (also called seborrheic dermatitis) is very common. In fact, about 11% of the population has this condition. We see it not just on the scalp, but also on the eyebrows, around the nose, on the ears and chest and around the mouth. Having dandruff doesn’t mean the skin is dirty or infected.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

Typically, we first treat seborrheic dermatitis with anti-dandruff shampoos that you can buy over the counter. For resistant cases, however, we may prescribe an antifungal product called ketoconazole (Nizoral®), available in a 2% formulation as a shampoo or cream. We may also prescribe you medicated foam, cream or solution.

What’s most important is to realize that this condition is intermittent and chronic — meaning it comes and goes over long periods of time. Continuing to use the medications recommended to you will help minimize the recurrence of this otherwise chronic condition.

— Dermatologist Christine Poblete-Lopez, MD

Advertisement

Cleveland Clinic icon
Health Essentials logo
Subscription icon

Better health starts here

Sign up for our Health Essentials emails for expert guidance on nutrition, fitness, sleep, skin care and more.

Learn more about our editorial process.

Related Articles

Hands combing wet hair with head lice comb
October 13, 2025/Skin Care & Beauty

Do Lice Jump? And Other Must-Know Facts

Lice don’t jump — but they can spread with direct head contact

Closeup of a head with scalp psoriasis
April 16, 2024/Skin Care & Beauty

Experiencing Scalp Psoriasis? Learn How To Treat and Reduce Hair Loss

Calm an itchy scalp by using medicated shampoo, avoiding blow-drying and resisting the urge to scratch

Back of person's head with long hair with hands scratching their scalp
December 11, 2023/Skin Care & Beauty

Itchy Scalp? 8 Common Causes and How To Find Relief

Options range from allergic reactions and head lice to chronic conditions and fungal infections

Concerned person holding handful of hair with extra hair in the brush
May 19, 2026/Skin Care & Beauty

Why Is My Hair Falling Out?

Natural shedding, alopecia and stress are just a few possible reasons for hair loss

Concerned woman in bedroom with hairbrush full of hair
May 19, 2026/Women’s Health

When To Worry About Hair Loss

Things like stress, heated styling and other health conditions may cause you to lose more hair than normal

Person applying oil to the ends of their hair
May 15, 2026/Skin Care & Beauty

Can the Sun Damage Your Hair?

Yes, but you can protect yourself with hats, scarves or even hair sunblock

Face of person, with coifed hair, and vitamins types and foods around
March 23, 2026/Skin Care & Beauty

The Best Vitamins and Supplements for Hair Growth

Iron, biotin and omega-3 fatty acids can help boost hair growth

Rosemary oil in glass bottle and fresh rosemary in wooden bowl
January 16, 2026/Skin Care & Beauty

Rosemary Oil for Your Hair: How It Works

Rosemary oil’s antioxidant, anti-inflammatory and antimicrobial properties could help stimulate hair growth

Trending Topics

Dry skin patch in background and person with eczema in foreground

Eczema vs. Dry Skin: What’s the Difference?

If you’re dealing with intense itching and red or swollen skin, it might be eczema

Panoramic X-ray of jaw and teeth

Teeth vs. Bones: Are They the Same?

While similar in some respects, teeth and bones have key differences, like durability and structure

Person applying olive oil on hand to get glue off skin

Sticky Situation: How To Get Super Glue Off Your Skin

Warm water, lotion, cooking oils or nail polish remover may all help to loosen the adhesive

Ad