February 13, 2023

Xeomin vs. Botox, and What To Know About Both

They both treat fine lines and wrinkles, but how they’re made and how long results last differ

Person getting a brow injection.

A hot topic in the skin community is a little thing called botulinum toxin. But you may know it by its stage name: Botox®.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

While this drug has been in use for the last 20 years, there’s a newer brand on the market that’s become a popular alternative for some: Xeomin®, otherwise known as botulinum toxin type A, or incobotulinumtoxinA.

What is Xeomin?

Dermatologist Chey Ranasinghe, MD, explains what Xeomin is, how it’s different from Botox and what to know about it.

Officially approved by the U.S. Federal Drug Administration (FDA) in 2010, Xeomin is the newest neuromuscular blocker on the market for various cosmetic and medical procedures.

First, here’s a quick refresher on neuromuscular blockers, in general. These are injectable drugs that are used to temporarily relax muscles in your face and sometimes, other parts of your body. In addition to cosmetic uses such as getting rid of fine lines and wrinkles, it can help with medical issues like migraines, overactive bladder and eye conditions.

Xeomin is similar to Botox and Dysport® in terms of its use,” says Dr. Ranasinghe.” It aims to temporarily relax the muscles that cause wrinkles, giving the skin a smoother and more youthful appearance.”

Xeomin vs. Botox

While they both have the same goal and are both applied through injection by needle, Xeomin isn’t a complete copy of Botox either. Here are some factors to compare when considering Botox or Xeomin:

How they’re made

The main distinction between Xeomin and Botox is how they’re manufactured. As Dr. Ranasinghe explains, Xeomin is a purified form of botulinum toxin type A, while Botox is composed of a complex mixture of proteins. Essentially, this means that Xeomin doesn’t have any additives, while Botox does. This is often why Xeomin is nicknamed the “naked injectable.”

What they treat

From aesthetic tweaks to the treatment of medical conditions, both Xeomin and Botox have a lot of overlap in what they can treat.

And both Xeomin and Botox have the same goal, and essentially can help with the same kind of needs, whether medical or cosmetic.

Advertisement

There are no specific conditions that Xeomin treats that Botox cannot,” notes Dr. Ranasinghe.

Xeomin and Botox have both been approved for cosmetic and medical use, including:

  • Wrinkles between your eyebrows.
  • Fine lines on your cheeks.
  • Cervical dystonia.
  • Neck spasms.
  • Eye twitching.
  • Arm spasms.

Benefits of Xeomin

So, why choose Xeomin versus Botox? It turns out there are a few reasons why you may opt for Xeomin over Botox — depending on your preference and needs.

Here are some benefits of using Xeomin over Botox:

Length of effects

When using neurotoxins for aesthetic purposes, the big plus for a lot of people is how long the effects last. If you’re getting certain areas of your face done, you may want to minimize the needed upkeep.

“The most notable benefit of using Xeomin over Botox is that the results last longer with Xeomin,” states Dr. Ranasinghe. “Results can last up to six months with Xeomin, compared to Botox results, which last for three to four months.”

Faster results

Next is the speed factor, which Xeomin seems to be known for as well.

Dr. Ranasinghe points out that while the desired results after Botox usually take around two weeks to show up, the results of Xeomin can be seen within three to five days. Depending on what you want and how quickly you want it, this could be a pro for you as well.

Advertisement

May cause fewer allergic reactions

With any kind of injection, you may be curious about possible side effects. While it’s rare, some people may also experience allergic reactions to Botox, like hives, itching or wheezing. Some have claimed that Xeomin can reduce that risk.

“With this purified form, the belief is that the risk for allergic reactions is also less with Xeomin compared to traditional Botox,” Dr. Ranasinghe adds.

At the moment, there aren’t any comparative studies between the two showing that Xeomin can have fewer side effects like swelling or headaches.

Possible side effects

Though Xeomin may lead to fewer allergic reactions than Botox, post-treatment side effects can still happen for both.

Both injectables can cause:

  • Bruising, redness and swelling at the injection site.
  • Bleeding.
  • Pain.
  • Itching.
  • Headache.

Is one better?

Whether or not one is better than the other is entirely up to your personal preferences. Another important consideration is that you shouldn’t use Botox and Xeomin interchangeably. The main reason many people still stick with Botox is that it’s been around for longer, it’s a more well-known brand and you may already have a history of using it and know how you’ll respond. It’s generally recommended to commit to one — which you can decide with help from your dermatologist.

“Both products are safe and effective options for improving the appearance of fine lines and wrinkles on the face,” reassures Dr. Ranasinghe. “The best choice for you will depend on your needs and concerns, along with consulting your physician.”

Related Articles

Person getting tape from a tape roll.
August 28, 2022
What Is Face Tape and Does It Work?

Using tape to smooth wrinkles may be a temporary fix, but there are still risks

Person recieving a botox injection in their leg.
July 26, 2022
Botox Treatment for Spasticity

The benefits go beyond cosmetic enhancements

edlerly woman getting botox injectin for wrinkle relief
January 27, 2022
How to Smooth Away Laugh Lines With or Without Surgery

What you can do for laugh lines and facial creases

Someone is getting a shot of botox in their armpit.
October 31, 2021
Can Botox Help You Sweat Less?

If you're tired of products that don’t stop your serious sweating, Botox could be life-changing

Closeup of dotted line indicating where eyelid lift will take place
February 14, 2024
Blepharoplasty vs. Brow Lift: What To Know

The procedures take different approaches to eliminate saggy, baggy skin around your eyes

jar of coconut oil-based cream next to a cut open coconut on a bath towel
February 9, 2024
Stop the Itch: Home Remedies To Help Manage Eczema

Colloidal oatmeal, petroleum jelly and other around-the-home products can help provide needed relief

stress factors floating around person with eczema on arms
February 8, 2024
Eczema and Stress: What’s the Connection?

Your body’s natural response to stress can lead to painful skin irritation

Smiling person holding small container of moisturizer close to face, with product applied to face
February 1, 2024
What Does Vitamin B5 Do for Your Hair and Skin?

Pantothenol is a powerful moisturizer and can help repair damaged skin and hair

Trending Topics

glass of cherry juice with cherries on table
Sleepy Girl Mocktail: What’s in It and Does It Really Make You Sleep Better?

This social media sleep hack with tart cherry juice and magnesium could be worth a try

Exercise and diet over three months is hard to accomplish.
Everything You Need To Know About the 75 Hard Challenge

Following five critical rules daily for 75 days may not be sustainable

Person in foreground standing in front of many presents with person in background holding gift bags.
What Is Love Bombing?

This form of psychological and emotional abuse is often disguised as excessive flattery

Ad