See where the deadliest skin cancer can develop
Think melanoma strikes only the typical sun-exposed areas of your skin? This deadly cancer can surface in surprising places, says dermatologist Christine Poblete-Lopez, MD:
Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy
Melanoma arises from melanocytes (cells that give us pigment). They are everywhere you’ve got skin. So, although it’s rare, melanoma can develop in your belly button, armpits and groin.
Yes, you also have melanocytes in your nail beds, feet and hands. Melanomas in these areas are more aggressive, likely due to a delay in diagnosis. They are more common among Asians and African-Americans.
Melanocytes also inhabit the colored iris of your eye, and you can develop melanoma there. When anyone develops melanoma, routine eye checks are as vital as skin checks.
It’s rare, but melanomas can develop in your body’s mucous membranes. These line your mouth, throat, genitalia, urinary tract, anus and rectum.
A full head of hair helps protect your scalp from the sun. But once hair starts to thin, melanoma can develop there, especially on the crown of the head.
You can’t blame melanoma entirely on the sun’s ultraviolet rays. Genetics also play a role. Multiple sunburns and exposure to tanning beds also increase your risk.
Apply sunscreen daily, just like you brush your teeth. Reapply it when going outdoors. For full protection, you should also wear sun-protective clothing, seek shade, and avoid direct sun between 10 a.m. and 3 p.m. (You can get vitamin D from supplements.)
Slide 1/7
Learn more about our editorial process.
The size, shape and color of moles may offer clues that point to melanoma
Family history matters for melanoma, but the connection isn’t as strong for other skin cancers
In some cases, itchiness can be a symptom of skin cancer
The who, what, why and how of skin checks
If you want clues about your overall health, look at your fingernails.
What you need to know about recurrence
Puffing on cigarettes is the leading cause of bladder cancer
You don’t have to cope in silence with issues like urinary incontinence and sexual dysfunction
Your metabolism may torch 1,300 to 2,000 calories daily with no activity
A gentle touch in all the right places may help drain your sinuses