Proper treatment should keep your skin tone more even
Congenital adrenal hyperplasia (CAH) affects hormones throughout your body, which can impact everything from your stress response and your electrolyte balance to how your physical features develop.
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It can also affect your skin. Acne is common, as are patches of uneven skin color called hyperpigmentation.
Endocrinologist Pratibha Rao, MD, shares how CAH can cause hyperpigmentation and what to do about it.
People with CAH can’t make (or don’t make enough) cortisol. That’s a hormone that, among other things, affects how your body responds to stress. When your body tries to compensate for missing cortisol, it creates a domino effect.
One thing leads to another, and other hormones are affected. Hyperpigmentation is one of those downstream changes.
Let’s take a close look at why:
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Hyperpigmentation is usually most noticeable on:
“Your natural skin tone can affect how hyperpigmentation shows,” Dr. Rao clarifies. “It can be less obvious on people with darker skin tones and more apparent on lighter skin.”
Now, for the good news: With proper management of CAH, patches of hyperpigmentation should fade away.
Glucocorticoids are a common category of medication for CAH. They replace the cortisol that your body doesn’t create naturally. These medications help do all the things that cortisol normally does — like help your body respond to stress and recover from injury.
They can also stop the cascade of hormone overproduction that leads to discolored patches.
“Glucocorticoids help to suppress ACTH. When you do that, you also keep the body from creating extra MSH,” Dr. Rao explains. “That means you don’t end up with hyperpigmentation either.”
Common glucocorticoids include:
Hyperpigmentation should start to clear up quickly after you begin taking glucocorticoids to manage CAH. Talk with a healthcare provider about how CAH is affecting you. Treatment is available to help you live your best life.
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