Locations:
Search IconSearch
September 9, 2021/Health Conditions/Digestive

Do Papaya Seeds Get Rid of Intestinal Parasites?

TikTok trend encourages eating papaya seeds to ‘deworm’

A close up of a person holding a slice of papaya fruit with the seeds

Nobody wants bugs in their butt. Consider that an explanation behind one of the latest trends — eating papaya seeds to eliminate stomach worms — wiggling around on TikTok.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

People are gobbling down the bitter fruit seeds in hopes of flushing unknown parasites out of their internal plumbing. Millions of videos posted on the social media channel share stories of… well, creepy-crawly worms evicted during the process.

So are papaya seeds the key to a parasite-free gut? And, realistically, how many people truly should worry about roundworms and other organisms inching through their intestinal tract?

We know what TikTokers say, but let’s check with a more reputable source — gastroenterologist Christine Lee, MD.

How common are intestinal parasites?

There’s a gross truth powering the TikTok trend: Roundworms such as toxocariasis, pinworms and ascariasis can take up residence in your intestines. The lifespan of these invaders ranges from weeks (pinworms) to up to two years (ascariasis).

Intestinal parasite infections affect tens of millions of people in the United States. Children are regular hosts given their sometimes less-than-stellar hygiene. They’re also seen in and spread by household pets such as dogs and cats.

Infections are more common for people living or spending time in impoverished areas or warmer climates. The parasites also can spread easily in institutional settings (such as schools or day cares) or when sewer and sanitation centers are compromised (broken water mains, hurricanes, power outages, etc.).

Advertisement

Roundworms typically enter your body through hand-to-mouth transfer. Infection can happen by touching soil or pet poop laden with roundworm eggs and then not washing your hands. (Again, a gross truth.)

The worms also could enter your system if you eat contaminated produce or undercooked meat (particularly pork) or drink untreated water.

Now the good news: Despite all of the above, intestinal parasites remain relatively uncommon in the United States. “They’re not unheard of,” says Dr. Lee, “but it’s not something that should be a regular concern for most people under normal circumstances.”

Do papaya seeds work against parasites?

The selection of papaya seeds as a natural cure for parasites didn’t just appear out of nowhere. There is some evidence that suggests the fruit could serve as a treatment tool against these body invaders.

A study published in 2007 is often highlighted to support the papaya seed theory. The study focused on 60 Nigerian children with evidence of intestinal parasites. Researchers reported that 71% of children who received papaya seeds as treatment cleared their stool of parasites.

Another study from 2014 identified papaya seeds as a potential alternative solution to eliminating parasites in goats. (That’s beneficial for goat farmers but not exactly an endorsement for at-home treatment for people.)

“These are small studies and should not be extrapolated to general use without quality randomized, controlled, prospective trials with larger sample sizes,” says Dr. Lee. “We need to know if papaya seeds really work and if they are safe for human use.”

There’s an additional concern about papaya seeds, too. Trace amounts of cyanide — a harmful natural chemical — exist on the seeds, says Dr. Lee. Given that, ingesting them in large quantities could be harmful to your health.

So what should you do if you have stomach worms?

If you think you’re among the unlucky ones with an unwanted intestinal guest, Dr. Lee offers this advice: Sign off from TikTok for a few minutes and schedule an appointment with your healthcare provider.

Symptoms of a parasite could include live worms being visible in your poop. (The gross truth continues.) Other symptoms include:

  • Diarrhea.
  • Nausea.
  • Unexplained weight loss.
  • Bleeding.
  • Anemia.
  • Gastric distress.

“These are classic alarm symptoms,” says Dr. Lee. “If in doubt, have it checked out.”

Treatment for hookworm usually includes a doctor’s prescription for a medication such as albendazole, mebendazole or pyrantel pamoate.

Dr. Lee emphasizes that papaya seeds or supplements touting deworming powers should not be relied upon as a primary form of treatment. “There is not adequate scientific evidence at this time to declare if this is effective or safe for human consumption,” she says.

Advertisement

Risks of self-diagnosing parasites

There’s an additional risk to assuming worms are behind stomach woes, per TikTok medical guidance: You may delay the diagnosis of the real culprit behind your symptoms, notes Dr. Lee.

Frequent diarrhea or a consistently rumbly tummy could be signs of numerous GI issues, including:

“With such a long and wide-ranging list of possibilities, getting the right diagnosis is very important to getting better,” says Dr. Lee.

Advertisement

Cleveland Clinic icon
Health Essentials logo
Subscription icon

Better health starts here

Sign up for our Health Essentials emails for expert guidance on nutrition, fitness, sleep, skin care and more.

Learn more about our editorial process.

Related Articles

Healthcare provider holding a tablet, talking to patient in medical setting
June 13, 2025/Digestive

Why You Should Avoid Colon Cleansing

It’s not an enema or bowel prep, and this colonic hydrotherapy can harm proper colon function

Assorted healthy foods spread out over a table and cutting boards
May 20, 2024/Digestive

What To Eat When You Have Diverticular Disease

Reducing inflammation is key when you’re in a flare-up, but so is having a preventive nutritional plan in place when you’re not

diverticulitis in the colon
January 27, 2020/Digestive

How Do You Treat ‘Smoldering Diverticulitis?’

The short answer from a colorectal surgeon

Person checking their health stats on their smartwatch, with checked off health goals, biohacking
June 17, 2026/Wellness

What To Know About Biohacking and How To Try It Safely

Practices range from simple lifestyle changes to extreme experiments — and not all approaches come with the same level of risk

Assorted high-fiber foods in bowls on table, like broccoli, beans, nuts and leafy greens
June 17, 2026/Nutrition

What Foods Are High in Fiber?

Eating more legumes, fruits, vegetables, nuts and whole grains can help you meet your daily fiber goals

Adult drinking glass of milk in kitchen
June 15, 2026/Nutrition

Is Dairy Milk Good for You?

Milk has long been considered a key part of a healthy diet, but moderation is important

Bottle and glass of soy milk, with soy beans scattered on table
June 9, 2026/Nutrition

Soy Milk Benefits: Why This Plant-Based Milk Stands Out

From protein to phytoestrogens, soy milk offers health benefits that many plant milks don’t

Cup of coffee and bowl of collagen peptide powder with spoon
June 8, 2026/Nutrition

What Are Collagen Peptides? And Do They Work?

Collagen peptide supplements may support your skin, joints and bones — but there’s no guarantee

Trending Topics

Peson sitting at table with laptop, elbows on table and hands at their temples

How To Get Past ‘Analysis Paralysis’

Simplifying choices, a reassuring attitude and avoiding information overload can help you overcome indecision

Person holding their nose in a smelly home

Is Thirdhand Smoke a Hidden Health Risk?

Nicotine and other lingering chemicals from smoking can harm people who don’t smoke, including children

Bottles of essential oils alongside plants

Essential Oils and Allergies: What the Science Says

The research is mixed, but experts agree: The risks outweigh the benefits

Ad