September 22, 2020

Recipe: Blackened Salmon With Avocado

Easy-to-make spice blend adds amazing flavor

Blackened salmon with avocados

This salmon dish is full of flavor, and it’s easy to make. You can have dinner ready in 15 minutes — especially if you make the spice mixture in advance. Serve with a garden salad and sliced avocados to add extra flavor, texture and healthy fats.


Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy


1 tablespoon smoked paprika
½ tablespoon sea salt
½ tablespoon freshly ground black pepper
1 tablespoon garlic powder
½ tablespoon onion powder
1 teaspoon cayenne pepper (or more, depending on preference for spice)
1 teaspoon cumin
1 teaspoon turmeric
2 teaspoons dried oregano
2 teaspoons dried thyme

For the Salmon

1 ½ tablespoons extra-virgin olive oil, divided
16 ounces boneless, skin-on wild salmon fillets, cut into 4 evenly sized fillets
1 avocado, quartered and sliced


  1. Preheat oven to 350°F.
  2. In a small mixing bowl combine spices. Reserve half of the seasoning and place the remaining seasoning in a glass jar. Leftover spice mix can be stored in a cool, dark place for up to 6 months.
  3. Combine the seasoning mix with ½ tablespoon of oil and stir to make a paste. Brush the flesh side of each fillet with the seasoning paste to coat evenly. If you have leftover paste, then brush the skin side of each fillet for enhanced flavor. You can add a bit more oil if your paste is too thick.
  4. In a large oven-safe skillet, heat the remaining oil on medium-high heat. When the oil is hot, place the salmon in the skillet flesh side down. You should hear a nice sizzle. Sear the fish for 2-3 minutes, without moving it. Turn the heat down to medium heat, flip the fish, and sear for another 2 minutes.
  5. Transfer the skillet to the oven and cook until fish is flaky and opaque (about 5 more minutes or until an internal temperature reaches 145° F).
  6. Remove from oven, let rest, and cool for about 5 minutes. Garnish with sliced avocado, and serve immediately with a side of greens.

Nutritional information

Serving size : 4 ounces salmon, ¼ avocado


Calories 310
Fat 20g
Saturated fat 4g
Cholesterol 50mg
Fiber 5g
Protein 26g
Carbohydrate 8g
Sodium 490mg

This recipe is from the book, Eat Fat, Get Thin, by Mark Hyman, MD

Related Articles

Oranges in bowl and tofu meal in bowl
December 8, 2023
Should You Take Iron With Vitamin C?

This pairing has long been thought to help your body better absorb iron

Buddha bowl of tofu, cucumbers, broccoli, lettuce and garbanzo beans
December 7, 2023
How To Make a Vegetarian Diet Work for a Healthier Heart

Giving up meat can have a significant effect on lowering cholesterol

Roasted Beets with Balsamic Vinegar and Herbs
December 5, 2023
Recipe: Roasted Beets With Balsamic Vinegar and Herbs

This colorful side dish will tantalize your taste buds

variety of food groups containing manganese and magnesium
November 30, 2023
Manganese vs. Magnesium: Two Important Minerals With Key Differences

They’re both essential minerals but do different jobs in your body

holy basil leaves, known as tulsi, on wooden spoon
November 30, 2023
The Benefits of Holy Basil (Tulsi)

This herb offers different potential benefits from the basil you find in pesto

cool tropical smoothie with straw
November 30, 2023
Recipe: Cool Tropical Smoothie

A zesty thirst-quencher that’s dairy-free and vegan

salmon and broccoli over rice
November 29, 2023
6 Foods To Eat for Healthy Joints

Fish, cruciferous veggies, turmeric, yogurt, ginger and green tea all reduce inflammation

skillet of ground turkey stroganoff
November 28, 2023
Recipe: Healthy Turkey Stroganoff

A hearty dish that’s easy to put together

Trending Topics

group of hands holding different beverages
November 14, 2023
10 Myths About Drinking Alcohol You Should Stop Repeating

Coffee won’t cure a hangover and you definitely shouldn’t mix your cocktail with an energy drink

Person applies moisturizer as part of their skin care routine after a shower.
November 10, 2023
Korean Skin Care Routines: What You Need To Know

Focus on the philosophy — replenishing and respecting your skin — not necessarily the steps

glass of cherry juice with cherries on table
November 8, 2023
Sleepy Girl Mocktail: What’s in It and Does It Really Make You Sleep Better?

This social media sleep hack with tart cherry juice and magnesium could be worth a try