Locations:
Search IconSearch

Why Vitamin K Can Be Dangerous If You Take Warfarin

Understand drug-food interactions

Illustration of blood clot in blood flowing through circulatory system

If you are a heart patient who is taking blood thinners, such as warfarin (Coumadin®), you need to be careful not to overdo vitamin K.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

Blood thinners are often prescribed for people at risk for developing harmful blood clots.

If you suddenly increase your intake of vitamin K, it can have an unintended consequence. It can actually decrease the effect of warfarin, says cardiologist Leslie Cho, MD.

“This is because vitamin K is an essential part of the chemical process for forming blood clots in your body,” she says.

Don’t cut vitamin K out completely

You don’t want to cut out vitamin K completely, as it is present in a variety of healthy, nutrient-rich foods. These include leafy greens and many vegetables. Instead, be smart about how much vitamin K you consume, be consistent, and work with your doctor to find just the right balance.

For example, if you eat a diet rich in vitamin K, you may need to check your blood a little more frequently or take more warfarin. If you change your diet and eat fewer foods containing vitamin K, you may need to take less warfarin.

Work with your doctor to find the right dose for you.

Here are three tips to help you safely manage your vitamin K intake:

1. Pay attention to food labels to keep your vitamin K intake consistent

“Vitamin K foods can be included in your diet on a regular basis as long as you are mindful of the portion and keep the overall intake of vitamin K-rich foods consistent, says Julia Zumpano, RD, LD.

Advertisement

For instance, you can choose to have a vitamin K rich food every day, every week, or three times in a week — as long as you keep this portion and frequency consistent, she says.

“If necessary, you can discuss including regular sources of vitamin K in your diet with your doctor in case your warfarin dosage would need to be adjusted,” she adds. You will want to tell your physician how often you eat foods high in vitamin K and how much of those foods you eat. Being knowledgeable about vitamin K is a key to managing it in your diet.

There are a variety of vegetables that contain lower amounts of vitamin K. These include:

Iceberg lettuce is low and romaine is also fairly low, so most people can eat either if them daily. In addition, be sure to read labels on multivitamins as they have varying amounts of vitamin K. Talk to your doctor about what vitamins you should take.

2. Beware of herbal supplements and omega-3 supplements (EPA/DHA)

You may need to avoid certain supplements and vitamins to keep your blood values stable. Talk to your doctor about any and all supplements you take to be sure they are not interfering with your blood thinners.

3. Take blood thinners in consistent way

Another way to manage how well your blood thinners work is to take your dose of warfarin at the same time each day, and from day to day, make sure your vitamin K intake is consistent, Dr. Cho says.

To be sure you’re on track, have your blood values checked regularly (usually once per month with your physician; this may be more often during dose adjusting).

Vitamin K in popular foods

Below, find more details on the amount of vitamin K present in different foods, including leafy greens, vegetables and other foods as provided by the U.S. Department of Agriculture.

When it comes to blood thinners, the more you know the better you can manage your diet. Be sure to talk to your doctor if you have any concerns.

Food chart with high to moderate vitamin K levels

Advertisement

Learn more about our editorial process.

Related Articles

anticoagulant pills
March 19, 2024/Primary Care
What To Avoid When Taking a Blood Thinner

Bleeding is a risk and warrants taking care, but the reward of this lifesaving medication is great

aspirin placed in the shape of a heart
January 21, 2021/Heart Health
Should You Take Aspirin If You Are on Blood Thinners?

The short answer from a cardiologist

Alfalfa sprouts in white bowl
December 23, 2025/Nutrition
4 Health Benefits of Alfalfa

These delicate green sprouts can give you an extra dose of vitamin K and other nutrients — but they’re not safe for everyone

Pregnant woman taking allergy pill, with glass of water
December 23, 2025/Pregnancy & Childbirth
Seasonal Allergy Medicine You Can Take When You’re Pregnant

Most antihistamines, like Zyrtec, are OK, but avoid decongestants for at least the first trimester

Assorted foods with vitamin C, including blueberries, broccoli, nuts and tomatoes
December 18, 2025/Nutrition
6 Benefits of Vitamin C — and How Much You Really Need

This powerful antioxidant does more than fight colds — it keeps you healthy inside and out

An uncapped GLP-1 injector on counter
December 18, 2025/Weight Loss
Does Ozempic Work for Weight Loss?

This diabetes medication can treat obesity, but it’s not for people who just want to drop a few pounds

Pile of salt with wooden scoop, with exclamation mark inside shape of a heart
December 16, 2025/Heart Health
How Does Salt Affect Heart Health?

Too much sodium can cause high blood pressure and increase your risk of heart disease

Heart-shaped soft-fried eggs on wheat toast
December 10, 2025/Heart Health
The Relationship Between Eggs, Cholesterol and Heart Health

Be mindful of how many eggs you’re eating, how you prepare them and the other sources of saturated fat in your diet

Trending Topics

Person looking at ovulation app on their smartphone
When Should You Have Sex To Get Pregnant?

Start having sex about 72 hours before ovulation, then at least every other day during your fertile window

Happy baby lying on back with hand in their mouth
What Is Attachment Theory? And How Does It Impact You?

Attachment theory suggests that your earliest relationships shape connections throughout your life

Person surrounded by social media podcasts and information
Is It Possible To Become Addicted to Social Media?

It isn’t a recognized mental health disorder, but research shows that problematic social media use can negatively affect your mental health, self-esteem and sleep

Ad