Locations:
Search IconSearch

What’s Best for Dandruff That Won’t Go Away?

The short answer from a dermatologist

Dandruff in hair
Learn three effective ways to manage dandruff.

Q: What do you recommend for resistant dandruff?

A: Skin or scalp dandruff (also called seborrheic dermatitis) is very common. In fact, about 11% of the population has this condition. We see it not just on the scalp, but also on the eyebrows, around the nose, on the ears and chest and around the mouth. Having dandruff doesn’t mean the skin is dirty or infected.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

Typically, we first treat seborrheic dermatitis with anti-dandruff shampoos that you can buy over the counter. For resistant cases, however, we may prescribe an antifungal product called ketoconazole (Nizoral®), available in a 2% formulation as a shampoo or cream. We may also prescribe you medicated foam, cream or solution.

What’s most important is to realize that this condition is intermittent and chronic — meaning it comes and goes over long periods of time. Continuing to use the medications recommended to you will help minimize the recurrence of this otherwise chronic condition.

— Dermatologist Christine Poblete-Lopez, MD

Advertisement

Cleveland Clinic icon
Health Essentials logo
Subscription icon

Better health starts here

Sign up for our Health Essentials emails for expert guidance on nutrition, fitness, sleep, skin care and more.

Learn more about our editorial process.

Related Articles

Person grimacing, scratching their head
June 18, 2026/Skin Care & Beauty

Itchy Scalp? Common Causes and Solutions

Dandruff, allergic reactions and lice can get you scratching your head

Hands combing wet hair with head lice comb
October 13, 2025/Skin Care & Beauty

Do Lice Jump? And Other Must-Know Facts

Lice don’t jump — but they can spread with direct head contact

Closeup of a head with scalp psoriasis
April 16, 2024/Skin Care & Beauty

Experiencing Scalp Psoriasis? Learn How To Treat and Reduce Hair Loss

Calm an itchy scalp by using medicated shampoo, avoiding blow-drying and resisting the urge to scratch

Carafe of olive oil, with person applying drops of olive oil to their hair
August 21, 2026/Skin Care & Beauty

Is Olive Oil Good for Your Hair?

A drizzle of olive oil may help your hair feel softer, shinier and less frizzy

Person emerging from the water sea side
August 12, 2026/Skin Care & Beauty

Is Saltwater Good for Your Hair and Skin?

Excessive exposure to saltwater can dehydrate skin and hair, despite having a few benefits

Person rinsing off in outdoor shower after swimming
August 12, 2026/Skin Care & Beauty

Protect Your Hair From Chlorine the Next Time You Go Swimming

A fresh water rinse before and after swimming can go a long way

Person looking in mirror, checking their hairline
July 15, 2026/Skin Care & Beauty

What Can You Do To Stop Your Hair From Thinning and Falling Out?

The sooner you address hair loss, the better your chances of preserving — and even regrowing — it

Man without hair looking out living room window
July 6, 2026/Skin Care & Beauty

Why Do Some Men Lose Their Hair?

Genetics, hormones and aging are usually responsible, but treatments can help slow hair loss and even encourage regrowth

Trending Topics

A fresh, sliced ube, with purple insides, and a fresh, whole ube

The Health Benefits of Ube

This vibrant purple yam offers vitamin C, fiber and antioxidants in every bite

Person rinsing off in outdoor shower after swimming

Protect Your Hair From Chlorine the Next Time You Go Swimming

A fresh water rinse before and after swimming can go a long way

Person selecting a piece of fresh salmon from a market case

Fish Faceoff: Wild Salmon vs. Farmed Salmon

Both are healthy choices, but wild-caught salmon offers a few more benefits

Ad