Locations:
Search IconSearch

When Should I Start Having My Cholesterol Checked? (Hint: Probably Sooner Than You Think)

Regular screening is vital to understanding your heart risk

Illustration of blood sample for cholesterol check

If you’re a healthy 20- or 30-something, you’re probably more concerned about work stress and finances than about your cholesterol. But it’s important to know your numbers — and it’s not something you should delay thinking about until middle age.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

Why? Because studies show that high cholesterol can have long-term effects on your heart health. And because it doesn’t have obvious symptoms, you could have it without knowing.

Why cholesterol screening is so important

Your body needs some cholesterol (a waxy, fat-like substance in your blood) to perform certain functions. But when there’s too much of it circulating in your blood, it can start to build up on the inside walls of your blood vessels, which restricts the flow of blood to your heart and brain. Eventually, this could cause a heart attack or stroke.

Statin therapy and certain lifestyle changes are effective ways to bring high cholesterol down to a healthy range. But most people won’t know that they have high cholesterol just by the way they feel.

That’s where screening comes in. “A lipid panel is an easy, inexpensive screening blood test that can be very helpful in identifying patients that are at risk for cardiovascular disease,” explains preventive cardiologist Luke Laffin, MD.

What is a lipid panel blood test?

A recent Cleveland Clinic survey found that only one in five Americans are aware that lipid panel cholesterol testing should begin in a person’s 20s, even if they don’t have symptoms of heart disease.

The latest guidelines from the American College of Cardiology and the American Heart Association call for healthy adults who do not have heart disease to have their cholesterol levels tested every four to six years, starting at age 20.

People who have heart disease or who are taking cholesterol-lowering medications, or those who have additional risk factors, may need to have it tested more often. Certain children who are at high risk for heart disease should also be screened.

Advertisement

Your primary care doctor can order this test. While there are cholesterol home test kits that can be purchased at drug stores or online, Dr. Laffin recommends against using them. “There’s too much variability in measurements from brand to brand,” he says. “I would recommend having this done by a professional laboratory.”

A lipid panel will measure some or all of the following:

  • Total cholesterol. Optimal total cholesterol level is < 200 mg/dL.
  • Low-density lipoprotein (LDL) cholesterol, also called “bad” cholesterol. The optimal LDL level is < 100 mg/dL.
  • High-density lipoprotein, also called “good” cholesterol. The optimal HDL level is > 60 mg/dL.
  • Triglycerides, which are another kind of fat molecule. The optimal level of triglycerides is < 150 mg/dL.

If your numbers do not fall into a healthy range, your doctor may prescribe a statin or recommend making some changes to your diet or lifestyle.

Cholesterol management is key in minimizing your risk for heart disease and stroke — but it’s important to remember that it is only one factor that contributes to your risk. Your doctor can work with you to determine your risk based on your cholesterol numbers plus other risk factors like family history, cigarette smoking, blood pressure and age.

Advertisement

Learn more about our editorial process.

Health Library
Cholesterol Levels

Related Articles

Hands holding pills/medications
November 26, 2025/Heart Health
How Statins Can Reduce Plaque Buildup

Medications known as statins can lower cholesterol levels to minimize the risk of blocked arteries

Person standing over table a food, holding small assorted bowl of nuts
November 20, 2025/Wellness
What Foods Should I Eat To Increase HDL Cholesterol?

Fatty fish, flaxseed, extra virgin olive oil and nuts may help raise your HDL number

Hand taking a grapefruit out of the fruit drawer in a fridge
September 8, 2025/Heart Health
Should You Avoid Grapefruit if You Take a Statin?

Grapefruit contains natural chemical compounds that can interfere with certain medications when it’s consumed in large amounts

Person checking medication information, sitting at kitchen table
April 30, 2025/Heart Health
Is My Statin To Blame for Muscle Pain?

Up to 30% of people who take the cholesterol-lowering medication feel aches and soreness

Orange capsules poured out of a bottle
January 17, 2025/Heart Health
Taking a Statin? Here’s Why You Don’t Need CoQ10 Supplements

There’s not enough evidence to show that this supplement has any effect on muscle aches from cholesterol-lowering meds

A server carries a platter full of nutritious foods
December 20, 2024/Nutrition
How Much Cholesterol Per Day Is Healthy?

There’s no limit on the amount you should have each day, but experts are focused on saturated fat

Person standing on scale in their bathroom, with measuring tape around waist
August 16, 2024/Heart Health
Do Statins Cause Weight Gain?

Statin use has been associated with weight gain but the reasons aren’t clear — and the benefits of statins far outweigh the risks

Oversized medical chart, glucose meter, pill bottle, with a normal-sized healthcare provider giving thumbs up
August 14, 2024/Heart Health
What’s the Connection Between Statins and Diabetes?

Some statins have been shown to slightly increase your risk of diabetes — but that shouldn’t keep you from taking the medication you need

Trending Topics

Assorted foods high in vitamin D, like salmon, with a vitamin D supplements
3 Foods High in Vitamin D

The ‘sunshine vitamin’ is found naturally in some fish and is added to other foods

Child standing on desk, disrupting the class
Understanding AuDHD

Autism and ADHD often go hand in hand, giving rise to the term AuDHD

Hands with red polished nails holding a packet of contraceptive, birth control pills
Can Your Birth Control Double as Emergency Contraception?

The Yuzpe regimen is less effective than other forms of emergency contraceptives, and it’s associated with more side effects

Ad