Locations:
Search IconSearch

5 Strange Places You Can Get Melanoma

See where the deadliest skin cancer can develop

Think melanoma strikes only the typical sun-exposed areas of your skin? This deadly cancer can surface in surprising places, says dermatologist Christine Poblete-Lopez, MD:

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

Melanoma arises from melanocytes (cells that give us pigment). They are everywhere you’ve got skin. So, although it’s rare, melanoma can develop in your belly button, armpits and groin.

Navel-Melanoma

Yes, you also have melanocytes in your nail beds, feet and hands. Melanomas in these areas are more aggressive, likely due to a delay in diagnosis. They are more common among Asians and African-Americans.

Nail-Melanoma

Melanocytes also inhabit the colored iris of your eye, and you can develop melanoma there. When anyone develops melanoma, routine eye checks are as vital as skin checks.

Eye-Melanoma

It’s rare, but melanomas can develop in your body’s mucous membranes. These line your mouth, throat, genitalia, urinary tract, anus and rectum.

Oral-Melanoma

A full head of hair helps protect your scalp from the sun. But once hair starts to thin, melanoma can develop there, especially on the crown of the head.

Scalp Melanoma

You can’t blame melanoma entirely on the sun’s ultraviolet rays. Genetics also play a role. Multiple sunburns and exposure to tanning beds also increase your risk.

Tanning Bed - open and lights switched on

Apply sunscreen daily, just like you brush your teeth. Reapply it when going outdoors. For full protection, you should also wear sun-protective clothing, seek shade, and avoid direct sun between 10 a.m. and 3 p.m. (You can get vitamin D from supplements.)

Advertisement

Applying sunscreen to arm

Advertisement

Cleveland Clinic icon
Health Essentials logo
Subscription icon

Better health starts here

Sign up for our Health Essentials emails for expert guidance on nutrition, fitness, sleep, skin care and more.

Learn more about our editorial process.

Related Articles

Dermatologist using magnifying tool to look at spot on person's back
December 11, 2024/Cancer Care & Prevention

What To Know About Recurrent Melanoma

The likelihood of melanoma returning varies by stage, but you can take steps to help prevent recurrence by wearing sunscreen and monitoring your moles

Caregiver applying makeup to smiling teen
March 31, 2026/Children’s Health

Is It OK for Your Kid To Wear Makeup? 5 Things To Consider

Educate your child about body image, expectations and skin care first

Healthcare provider checking moles on person's shoulder

Is That Mole Cancerous?

The size, shape and color of moles may offer clues that point to melanoma

Gloved hands of a tattooist using a tattoo iron to apply a tattoo
March 20, 2026/Skin Care & Beauty

Tattoo Aftercare Tips From a Dermatologist

Help your ink heal by keeping it moisturized and protected from the sun

Hands mixing ground coffee beans and lotion for a face mask
March 18, 2026/Skin Care & Beauty

Is Coffee Good for Your Skin?

Coffee skin care products contain anti-aging and brightening benefits — but there may be better options

Hands squeezing their upper thigh to show cellulite
March 12, 2026/Skin Care & Beauty

Can You Get Rid of Cellulite?

A healthy diet, regular exercise and in-office treatments may help minimize the dimply appearance

Person applying lotion to eczema rash on hands
February 19, 2026/Skin Care & Beauty

Having an Eczema Flare-Up? Here’s What To Do

Eczema triggers are different for everyone, but there are some common ways to manage flare-ups, like using a humidifier and fragrance-free creams

Ringworm on the skin, with a smear of antifungal cream by it, ready to be rubbed in
February 11, 2026/Skin Care & Beauty

How To Get Rid of Ringworm: A Quick Guide

Over-the-counter antifungal creams usually get the job done, but it’s important to keep it from spreading in the meantime

Trending Topics

Person getting a mammogram under direction of radiologist

How To Reduce Risk of Breast Cancer

While you can’t change risk factors, like age or genetics, lifestyle choices and regular screenings can help lower your overall risk

Cold hands clasped together and cold feet in socks

7 Reasons Why Your Hands and Feet Are Always Cold

While it may be no big deal, underlying conditions that need treatment can also cause cold extremities

Person running fast on outdoor track

How To Become a Faster Runner

Improve your speed with interval training, strength training and consistent, healthy habits

Ad