Locations:
Search IconSearch

Recipe: Tofu Manicotti With Spinach and Cheese

Enjoy a lighter option of this classic Italian fare

Two tofu-stuffed manicotti displayed on a bed of sliced tomatoes

This tofu manicotti will melt in your mouth, yet it only has 2 grams of fat per serving. Low-fat melted cheeses, spinach and tofu nestled in whole-wheat manicotti shells offer a lighter option when you’re craving rich Italian fare.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

Ingredients

  • 12 manicotti shells (8 ounces), preferably whole wheat
  • One 12.3-ounce container light silken tofu, drained and mashed
  • 1/4 cup egg substitute
  • One 15-ounce container reduced-fat ricotta cheese
  • One 10-ounce package frozen chopped spinach, thawed and well-drained
  • 1 1/2 cups grated fat-free mozzarella cheese
  • 1/4 cup chopped fresh basil, or 2 tablespoons dried
  • 3 cups tomato sauce
  • 2 tablespoons freshly grated Parmesan cheese

Directions

  1. Preheat oven to 350 F.
  2. Boil the manicotti shells according to package directions. Drain and set aside to cool.
  3. Combine the tofu, egg substitute, ricotta, spinach, mozzarella and basil in a bowl. Stir until just combined. Pour 2 cups of the tomato sauce into a 13 x 9 x 2 baking dish. Carefully stuff the manicotti shells with the tofu mixture and arrange in the dish. Top with the remaining tomato sauce. (The shells can be made up to one day ahead, covered with aluminum foil and refrigerated until ready to bake).
  4. Cover with aluminum foil and bake for 25 minutes. Uncover, sprinkle with Parmesan cheese and bake for 5 minutes, or until the cheese has melted. (If refrigerated, bake, covered for 50 minutes before sprinkling with Parmesan). Allow the manicotti to rest for 5 minutes before serving.

Advertisement

Ingredient health benefits

  • Tofu: Like a kind of culinary chameleon, tofu can be added to just about any dish and taste great, but there’s more to this soft, versatile soy product than meets the eye. Tofu is full of flavonoids that promote your heart and brain health, and it’s a plant-based complete protein that provides your body with the amino acids it can’t make on its own. You may be surprised to learn that tofu is also packed with crucial vitamins and minerals like vitamin B5 (pantothenic acid), iron and copper, as well as calcium and magnesium for sturdy bones. And contrary to the popular belief about soy, tofu may actually help decrease your risk of developing certain cancers in a well-balanced eating plan.
  • Cheese: Your taste buds aren’t the only body parts that benefit from some delicious dairy! Cheese has two main proteins, casein and whey. These help build and maintain healthy muscles. It’s also a vegetarian-friendly complete protein that’s packed with heart-helpful omega-3s, as well as vitamin A and vitamin B12. There are even notable minerals like selenium and zinc, which help balance vital hormones and bolster your immune response.
  • Spinach: There are a lot of benefits stuffed into this salad favorite. For starters, spinach is ridiculously high in vitamin K (two-thirds of a cup provides 402% of your daily value) and a good source of manganese, which work together to help your body build strong bones and keep your blood cells happy. This leafy green is also rich in vitamin A, lutein and beta-carotene — nutrients that are essential for maintaining good vision and healthy eyes. But wait, there’s more! Spinach has folate (vitamin B9) and potassium for your heart and brain, as well as immunity-promoting vitamin C. And let’s not forget how a bit of insoluble fiber can do wonders for your gut health.
  • Basil: A timeless and tasty herb, basil isn’t just for enhancing the flavor of your recipe. There’s also vitamin K, as well as antioxidants that fight cell damage from harmful little particles called free radicals. Basil may support your brain and your mental health by helping to improve your memory and mood while lowering anxiety and stress. And while more research is needed, there’s a possibility that natural compounds in basil may have cancer-fighting properties.

Nutrition information (per serving)

Servings = 6


Calories: 340
Total fat: 4 g
Saturated Fat: 2 g
Cholesterol: 24 mg
Sodium: 447 mg
Total fiber: 5 g
Protein: 29 g
Carbohydrates: 45 g

Cleveland Clinic Healthy Heart Lifestyle Guide and Cookbook (© 2007 Broadway Books).

Advertisement

Learn more about our editorial process.

Related Articles

Plate of indian-inspired cauliflower
January 2, 2025/Recipes
Recipe: Spicy Indian-Inspired Cauliflower

A flavorful side dish featuring South Asian spices

Plate of roasted winter vegetables, with Brussels sprouts, peppers , onions
December 26, 2024/Recipes
Recipe: Roasted Winter Vegetable Ragout

You can enjoy this colorful vegetable medley all winter long

Large bowl of holiday cabbage slaw with apples and cranberries
December 24, 2024/Recipes
Recipe: Holiday Cabbage Slaw With Dried Cranberries

This tasty holiday salad will wow you

White crock of butternut, carrot and ginger soup on plate
December 12, 2024/Recipes
Recipe: Butternut Squash, Carrot and Ginger Soup

Creamy and sweetly satisfying

Bowl of creamy broccoli soup with cheese
December 10, 2024/Recipes
Recipe: Lighter Creamy Broccoli Soup

Low in calories, high in flavor

A bright orange ceramic pot full of white bean stew with rosemary and spinach, with spoons and crock lid on table
December 5, 2024/Recipes
Recipe: White Bean Stew With Rosemary and Spinach

This hearty soup is full of nutrients and ready in 30 minutes

Bowl of soba noodles with veggies and tofu, with chopsticks across top of bowl
November 14, 2024/Recipes
Recipe: Veggie Stir-Fry in Sweet Ginger Sauce

Vegan recipe with tofu and soba noodles

Crock of creole black beans and tomatoes
November 12, 2024/Recipes
Recipe: Creole Black Beans With Tomatoes

A versatile, easy and satisfying main dish

Trending Topics

Person in bed sleeping on their side, covers off
Breathing Problems? Try These Sleep Positions

If you’re feeling short of breath, sleep can be tough — propping yourself up or sleeping on your side may help

A couple looking at skyline, with one person slightly behind the other, head bent down
What Is Anxious Attachment Style — and Do You Have It?

If you fear the unknown or find yourself needing reassurance often, you may identify with this attachment style

Glasses and bottle of yellow-colored prebiotic soda, with mint, lemon and ginger garnish
Are Prebiotic Sodas Good for You?

If you’re looking to boost your gut health, it’s better to get fiber from whole foods

Ad